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Diagnostic and economic evaluation of new biomarkers for Alzheimer’s disease: the research protocol of a prospective cohort study

  • Ron LH Handels1,
  • Pauline Aalten1,
  • Claire AG Wolfs1,
  • Marcel OldeRikkert2,
  • Philip Scheltens3,
  • Pieter Jelle Visser1, 3,
  • Manuela A Joore4,
  • Johan L Severens4, 5 and
  • Frans RJ Verhey1, 6Email author
BMC Neurology201212:72

DOI: 10.1186/1471-2377-12-72

Received: 1 November 2011

Accepted: 31 July 2012

Published: 10 August 2012

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
1 Nov 2011 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
24 Jul 2012 Author responded Author comments - Ron Leonardus Hubertus Handels
Resubmission - Version 3
24 Jul 2012 Submitted Manuscript version 3
31 Jul 2012 Editorially accepted
10 Aug 2012 Article published 10.1186/1471-2377-12-72

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

Alzheimer Centre Limburg, School for Mental Health and Neuroscience (MHeNS), University Medical Centre
Alzheimer Centre Nijmegen, Radboud University Nijmegen Medical Centre
Alzheimer Centre, Department of Neurology, VU University Medical Centre
Department of Health Organization, Policy and Economics, Maastricht University, CAPHRI School for Public Health and Primary Care, Faculty of Health Medicine and Life Sciences
Institute of Health Policy and Management, Erasmus University Rotterdam
Department of Psychiatry and Neuropsychology, University Hospital of Maastricht/Alzheimer Centre Limburg