Section edited by Ravindra kumar Garg

This section is dedicated to epilepsy and seizures. Topics of interest include any condition where the main manifestations are seizures (epileptic or not), whether the issues studied pertain to diagnosis or management.

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  1. Research article

    Health care cost associated with the use of enzyme-inducing and non-enzyme–active antiepileptic drugs in the UK: a long-term retrospective matched cohort study

    Some antiepileptic drugs (AEDs) induce expression of hepatic enzymes. This can contribute to comorbidities via interference with metabolic pathways and concomitant drug metabolization, thereby increasing the l...

    Simon Borghs, Solène Thieffry, Matthias Noack-Rink, Peter Dedeken, Lai San Hong, Laura Byram, John Logan, Jane Chan and Victor Kiri

    BMC Neurology 2017 17:59

    Published on: 23 March 2017

  2. Research article

    Mindfulness-based interventions in epilepsy: a systematic review

    Mindfulness based interventions (MBIs) are increasingly used to help patients cope with physical and mental long-term conditions (LTCs). Epilepsy is associated with a range of mental and physical comorbidities...

    Karen Wood, Maggie Lawrence, Bhautesh Jani, Robert Simpson and Stewart W. Mercer

    BMC Neurology 2017 17:52

    Published on: 20 March 2017

  3. Research article

    Syncope and Epilepsy coexist in ‘possible’ and ‘drug-resistant’ epilepsy (Overlap between Epilepsy and Syncope Study - OESYS)

    Differential diagnosis between syncope and epilepsy in patients with transient loss of consciousness of uncertain etiology is still unclear. Thus, the aim of the present work is to evaluate the prevalence of s...

    Andrea Ungar, Alice Ceccofiglio, Francesca Pescini, Chiara Mussi, Gianni Tava, Martina Rafanelli, Assunta Langellotto, Niccolò Marchionni, J. Gert van Dijk, Gianlugi Galizia, Domenico Bonaduce and Pasquale Abete

    BMC Neurology 2017 17:45

    Published on: 28 February 2017

  4. Research article

    Relationship between ABCB1 3435TT genotype and antiepileptic drugs resistance in Epilepsy: updated systematic review and meta-analysis

    Antiepileptic drugs (AEDs) are effective medications available for epilepsy. However, many patients do not respond to this treatment and become resistant. Genetic polymorphisms may be involved in the variation...

    Malek Chouchi, Wajih Kaabachi, Hedia Klaa, Kalthoum Tizaoui, Ilhem Ben-Youssef Turki and Lamia Hila

    BMC Neurology 2017 17:32

    Published on: 15 February 2017

  5. Case report

    Dancing with a seizure, a case report

    Dancing is a very rare seizure semiology, and has only few case reports so far. Moreover, no case regarded as dancing with both description and video was presented.

    Keun Tae Kim, Kon Chu and Sang Kun Lee

    BMC Neurology 2017 17:16

    Published on: 25 January 2017

  6. Research article

    Prevalence of non-febrile seizures in children with idiopathic autism spectrum disorder and their unaffected siblings: a retrospective cohort study

    Autism spectrum disorder (ASD) is a heterogeneous disorder characterized not only by deficits in communication and social interactions but also a high rate of co-occurring disorders, including metabolic abnorm...

    Lena M. McCue, Louise H. Flick, Kimberly A. Twyman, Hong Xian and Thomas E. Conturo

    BMC Neurology 2016 16:245

    Published on: 28 November 2016

  7. Research article

    The network sustaining action myoclonus: a MEG-EMG study in patients with EPM1

    To explore the cortical network sustaining action myoclonus and to found markers of the resulting functional impairment, we evaluated the distribution of the cortico-muscular coherence (CMC) and the frequency ...

    Silvana Franceschetti, Laura Canafoglia, Fabio Rotondi, Elisa Visani, Alice Granvillano and Ferruccio Panzica

    BMC Neurology 2016 16:214

    Published on: 7 November 2016

  8. Research article

    Ethiopian teachers: their knowledge, attitude and practice towards epilepsy

    In Ethiopia where the burden of epilepsy is highest among school age children and teenagers, and where people with epilepsy (PWE) and their relatives suffers from high level of perceived stigma, there had not ...

    Meron Awraris Gebrewold, Fikre Enquselassie, Redda Teklehaimanot and Seid Ali Gugssa

    BMC Neurology 2016 16:167

    Published on: 8 September 2016

  9. Research article

    Comparative effectiveness of levetiracetam, valproate and carbamazepine among elderly patients with newly diagnosed epilepsy: subgroup analysis of the randomized, unblinded KOMET study

    Few clinical trials have evaluated the efficacy and tolerability of antiepileptic drugs (AEDs) as initial monotherapy for elderly patients.

    Bernd Pohlmann-Eden, Anthony G. Marson, Matthias Noack-Rink, Francisco Ramirez, Azita Tofighy, Konrad J. Werhahn, Imane Wild and Eugen Trinka

    BMC Neurology 2016 16:149

    Published on: 23 August 2016

  10. Research article

    The economic impact of epilepsy: a systematic review

    In this review we aimed to determine the economic impact of epilepsy and factors associated with costs to individuals and health systems.

    Katharina Allers, Beverley M. Essue, Maree L. Hackett, Janani Muhunthan, Craig S. Anderson, Kristen Pickles, Franziska Scheibe and Stephen Jan

    BMC Neurology 2015 15:245

    Published on: 25 November 2015

  11. Research article

    Asystole in the epilepsy unit

    Early identification of cardiac asystole as a reason for syncope is of uttermost significance, as insertion of a cardiac pacemaker can save the patient’s life and prevent severe injury. The aim of this work wa...

    Asaf Honig, Shmuel Chen, Felix Benninger, Rima Bar-Yossef, Roni Eichel, Svetlana Kipervasser, Ilan Blatt, Miri Y. Neufeld and Dana Ekstein

    BMC Neurology 2015 15:80

    Published on: 14 May 2015

  12. Research article

    Efficacy and safety of conversion to monotherapy with eslicarbazepine acetate in adults with uncontrolled partial-onset seizures: a historical-control phase III study

    Eslicarbazepine acetate (ESL, Aptiom®) is a once-daily (QD) anticonvulsant, approved as adjunctive treatment of partial-onset seizures (POS). It is extensively converted after oral administration to eslicarbaz...

    Mercedes P Jacobson, Ladislav Pazdera, Perminder Bhatia, Todd Grinnell, Hailong Cheng and David Blum

    BMC Neurology 2015 15:46

    Published on: 28 March 2015

  13. Study protocol

    (Cost)-effectiveness of a multi-component intervention for adults with epilepsy: study protocol of a Dutch randomized controlled trial (ZMILE study)

    In patients with epilepsy, poor adherence to anti-epileptic drugs has been shown to be the most important cause of poorly controlled epilepsy. Furthermore, it has been noted that the quality of life among pati...

    Loes AM Leenen, Ben FM Wijnen, Reina JA de Kinderen, Marian HJM Majoie, Caroline M van Heugten and Silvia MAA Evers

    BMC Neurology 2014 14:255

    Published on: 24 December 2014

  14. Case report

    Positivity to p-ANCA in patients with status epilepticus

    Status epilepticus (SE) may occur in the setting of several internal or neurologic diseases. Anti-neutrophilic cytoplasmic antibodies (ANCA) are a group of Ig that may be observed in patients with different au...

    Edoardo Ferlazzo, Antonio Gambardella, Marina Bellavia, Sara Gasparini, Laura Mumoli, Angelo Labate, Vittoria Cianci, Concetta Russo and Umberto Aguglia

    BMC Neurology 2014 14:148

    Published on: 17 July 2014

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