Neurocritical care

Section edited by Andreas Meisel

This section covers life-threatening diseases of the central or peripheral nervous systems. Topics include, but are not limited to, coma, status epilepticus, intracranial hemorrhages, neurotrauma, delirium, metabolic encephalopathies, severe stroke, anoxic-ischemic encephalopathy, central nervous system infections and inflammations, Guillain-Barre syndrome, myasthenia gravis crises, intoxications and withdrawal states.

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  1. Research article

    Neurocognitive function in HIV-infected persons with asymptomatic cryptococcal antigenemia: a comparison of three prospective cohorts

    HIV-infected persons with detectable cryptococcal antigen (CrAg) in blood have increased morbidity and mortality compared with HIV-infected persons who are CrAg-negative. This study examined neurocognitive fun...

    Martha P. Montgomery, Noeline Nakasujja, Bozena M. Morawski, Radha Rajasingham, Joshua Rhein, Elizabeth Nalintya, Darlisha A. Williams, Kathy Huppler Hullsiek, Agnes Kiragga, Melissa A. Rolfes, Renee Donahue Carlson, Nathan C. Bahr, Kate E. Birkenkamp, Yukari C. Manabe, Paul R. Bohjanen, Jonathan E. Kaplan…

    BMC Neurology 2017 17:110

    Published on: 12 June 2017

  2. Research article

    The effects of video game therapy on balance and attention in chronic ambulatory traumatic brain injury: an exploratory study

    Patients with traumatic brain injury often have balance and attentive disorders. Video game therapy (VGT) has been proposed as a new intervention to improve mobility and attention through a reward-learning app...

    Sofia Straudi, Giacomo Severini, Amira Sabbagh Charabati, Claudia Pavarelli, Giulia Gamberini, Anna Scotti and Nino Basaglia

    BMC Neurology 2017 17:86

    Published on: 10 May 2017

  3. Case report

    Cortical laminar necrosis in dengue encephalitis—a case report

    Dengue encephalitis is a rare neurological manifestation of dengue fever. Its clinical presentation is similar to other viral encephalitides and encephalopathy. No single specific finding on magnetic resonance...

    Ravindra Kumar Garg, Imran Rizvi, Rajan Ingole, Amita Jain, Hardeep Singh Malhotra, Neeraj Kumar and Dhruv Batra

    BMC Neurology 2017 17:79

    Published on: 20 April 2017

  4. Technical advance

    Process for developing rehabilitation practice recommendations for individuals with traumatic brain injury

    Attempts at measuring quality of rehabilitation care are hampered by a gap in knowledge translation of evidence-based approaches and lack of consensus on best practices. However, adoption of evidence-based bes...

    Librada Callender, Rachel Brown, Simon Driver, Marie Dahdah, Ashley Collinsworth and Shahid Shafi

    BMC Neurology 2017 17:54

    Published on: 20 March 2017

  5. Research article

    Outcome of neurological early rehabilitation patients carrying multi-drug resistant bacteria: results from a German multi-center study

    Colonization or infection with multi-drug resistant (MDR) bacteria is considered detrimental to the outcome of neurological and neurosurgical early rehabilitation patients.

    J. D. Rollnik, M. Bertram, C. Bucka, M. Hartwich, M. Jöbges, G. Ketter, B. Leineweber, M. Mertl-Rötzer, D. A. Nowak, T. Platz, K. Scheidtmann, R. Thomas, F. von Rosen, C. W. Wallesch, H. Woldag, P. Peschel…

    BMC Neurology 2017 17:53

    Published on: 20 March 2017

  6. Research article

    What is the optimal sequence of decompression for multilevel noncontinuous spinal cord compression injuries in rabbits?

    In recent years, multilevel spinal cord injuries (SCIs) have gained a substantial amount of attention from clinicians and researchers. Multilevel noncontinuous SCI patients cannot undergo the multiple steps of...

    Chaohua Yang, Baoqing Yu, Fenfen Ma, Huiping Lu, Jianmin Huang, Qinghua You, Bin Yu, Jianlan Qiao and Jianjun Feng

    BMC Neurology 2017 17:44

    Published on: 23 February 2017

  7. Case report

    Case report: subacute tetraplegia in an immunocompromised patient

    Clinical reasoning in Neurology is based on general associations which help to deduce the site of the lesion. However, even “golden principles” may occasionally be deceptive. Here, we describe the case of suba...

    Daniel Zeller, Anke Heidemeier, Götz Ulrich Grigoleit and Wolfgang Müllges

    BMC Neurology 2017 17:31

    Published on: 10 February 2017

  8. Research article

    Why use a mirror to assess visual pursuit in prolonged disorders of consciousness? Evidence from healthy control participants

    Evidence of reliable smooth visual pursuit is crucial for both diagnosis and prognosis in prolonged disorders of consciousness (PDOC). However, a mirror is more likely than an object to elicit evidence of smoo...

    Damian Cruse, Marco Fattizzo, Adrian M. Owen and Davinia Fernández-Espejo

    BMC Neurology 2017 17:14

    Published on: 24 January 2017

  9. Case report

    Ischaemic stroke and Clostridium septicum sepsis and meningitis in a patient with occult colon carcinoma - a case report and review of the literature

    Clostridium septicum is a rare cause of meningitis and brain abscess in children and adults. Gas production by the pathogen can lead to pneumocephalus and the overall mortality rate of Clostridium septicum CNS in...

    Kosmas Macha, Antje Giede-Jeppe, Hannes Lücking, Roland Coras, Hagen B. Huttner and Jürgen Held

    BMC Neurology 2016 16:239

    Published on: 24 November 2016

  10. Research article

    Predictive value of the Status Epilepticus Severity Score (STESS) and its components for long-term survival

    The “Status Epilepticus Severity Score” (STESS) is the most important clinical score to predict in-hospital mortality of patients with status epilepticus (SE), but its prognostic relevance for long-term surviv...

    Preben Aukland, Martin Lando, Ole Vilholm, Elsebeth Bruun Christiansen and Christoph Patrick Beier

    BMC Neurology 2016 16:213

    Published on: 5 November 2016

  11. Research article

    Somatic survival and organ donation among brain-dead patients in the state of Qatar

    The Qatari law, as in many other countries, uses brain death as the main criteria for organ donation and cessation of medical support. By contrast, most of the public in Qatar do not agree with the limitation ...

    Saibu George, Merlin Thomas, Wanis H. Ibrahim, Ahmed Abdussalam, Prem Chandra, Husain Shabbir Ali and Tasleem Raza

    BMC Neurology 2016 16:207

    Published on: 31 October 2016

  12. Research article

    Effects of clobazam for treatment of refractory status epilepticus

    Clobazam (CLB) is a well characterized antiepileptic drug (AED) that differs from other benzodiazepines by its basic chemical structure and pharmacodynamic properties. Only one previous study examined the effi...

    Dominik Madžar, Anna Geyer, Ruben U. Knappe, Stephanie Gollwitzer, Joji B. Kuramatsu, Stefan T. Gerner, Hajo M. Hamer and Hagen B. Huttner

    BMC Neurology 2016 16:202

    Published on: 21 October 2016

  13. Research article

    Assessment of primary rehabilitation needs in neurological rehabilitation: translation, adaptation and face validity of the Danish version of Rehabilitation Complexity Scale-Extended

    Assessing primary rehabilitation needs in patients with acquired brain injury is a challenge due to case complexity and the heterogeneity of symptoms after brain injury. The Rehabilitation Complexity Scale-Ext...

    Thomas Maribo, Asger R. Pedersen, Jim Jensen and Jørgen F. Nielsen

    BMC Neurology 2016 16:205

    Published on: 21 October 2016

  14. Case report

    Evolution of severe sleep-wake cycle disturbances following traumatic brain injury: a case study in both acute and subacute phases post-injury

    Sleep-wake disturbances are frequently reported following traumatic brain injury (TBI), but they remain poorly documented in the acute stage of injury. Little is known about their origin and evolution.

    Catherine Duclos, Marie Dumont, Marie-Julie Potvin, Alex Desautels, Danielle Gilbert, David K Menon, Francis Bernard and Nadia Gosselin

    BMC Neurology 2016 16:186

    Published on: 27 September 2016

  15. Research article

    Sympathetic activity and early mobilization in patients in intensive and intermediate care with severe brain injuries: a preliminary prospective randomized study

    Patients who experience severe brain injuries are at risk of secondary brain damage, because of delayed vasospasm and edema. Traditionally, many of these patients are kept on prolonged bed rest in order to mai...

    A. Rocca, J.-M. Pignat, L. Berney, J. Jöhr, D. Van de Ville, R. T. Daniel, M. Levivier, L. Hirt, A. R. Luft, E. Grouzmann and K. Diserens

    BMC Neurology 2016 16:169

    Published on: 13 September 2016

  16. Research article

    Adjunctive dexamethasone therapy in unconfirmed bacterial meningitis in resource limited settings: is it a risk worth taking?

    Bacterial meningitis is associated with significant morbidity and mortality despite advances in medical care. The main objective of this study was to assess the association of adjunctive dexamethasone treatmen...

    Esayas Kebede Gudina, Markos Tesfaye, Aynishet Adane, Kinfe Lemma, Tamiru Shibiru, Andreas Wieser, Hans-Walter Pfister and Matthias Klein

    BMC Neurology 2016 16:153

    Published on: 26 August 2016

  17. Research article

    Regional homogeneity changes between heroin relapse and non-relapse patients under methadone maintenance treatment: a resting-state fMRI study

    Methadone maintenance treatment (MMT) is recognized as one of the most effective treatments for heroin addiction but its effect is dimmed by the high incidence of heroin relapse. However, underlying neurobiolo...

    Haifeng Chang, Wei Li, Qiang Li, Jiajie Chen, Jia Zhu, Jianjun Ye, Jierong Liu, Zhe Li, Yongbin Li, Ming Shi, Yarong Wang and Wei Wang

    BMC Neurology 2016 16:145

    Published on: 18 August 2016

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