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  1. Research article

    Voxel-wise correlations between cognition and cerebral blood flow using arterial spin-labeled perfusion MRI in patients with Alzheimer’s disease: a cross-sectional study

    To analyze voxel-wise correlation between cerebral blood flow (CBF) measured using ASL-MRI and cognition in patients with Alzheimer’s disease (AD).

    Tomohiro Kaneta, Omi Katsuse, Takamasa Hirano, Matsuyoshi Ogawa, Ayako Shihikura-Hino, Keisuke Yoshida, Toshinari Odawara, Yoshio Hirayasu and Tomio Inoue

    BMC Neurology 2017 17:91

    Published on: 15 May 2017

  2. Case report

    A possible role of low regulatory T cells in anti-acetylcholine receptor antibody positive myasthenia gravis after bone marrow transplantation

    Chronic graft-versus-host disease (GVHD) appears several months following allogenic hematopoietic stem cell transplantation (HSCT) and is clinically analogous to autoimmune disorder. Polymyositis is a common n...

    Masahiko Fukatsu, Takenobu Murakami, Hiroshi Ohkawara, Shunichi Saito, Kazuhiko Ikeda, Suguru Kadowaki, Itaru Sasaki, Mari Segawa, Tomoko Soeda, Akihiko Hoshi, Hiroshi Takahashi, Akiko Shichishima-Nakamura, Kazuei Ogawa, Yoshihiro Sugiura, Hitoshi Ohto, Yasuchika Takeishi…

    BMC Neurology 2017 17:93

    Published on: 15 May 2017

  3. Research article

    Transcranial doppler sonography is not a valid diagnostic tool for detection of basilar artery stenosis or in-stent restenosis: a retrospective diagnostic study

    There are contradictory reports concerning the validity of transcranial sonography (TCD and TCCS) for examinations of the basilar artery. Here we investigated sensitivity and specificity of transcranial sonogr...

    Woori Koh, Kai Kallenberg, André Karch, Tobias Frank, Michael Knauth, Mathias Bähr and Jan Liman

    BMC Neurology 2017 17:89

    Published on: 11 May 2017

  4. Research article

    A diagnostic biomarker profile for fibromyalgia syndrome based on an NMR metabolomics study of selected patients and controls

    Fibromyalgia syndrome (FMS) is a chronic pain syndrome. A plausible pathogenesis of the disease is uncertain and the pursuit of measurable biomarkers for objective identification of affected individuals is a c...

    Bontle G. Malatji, Helgard Meyer, Shayne Mason, Udo F.H. Engelke, Ron A. Wevers, Mari van Reenen and Carolus J. Reinecke

    BMC Neurology 2017 17:88

    Published on: 11 May 2017

  5. Research article

    The effects of video game therapy on balance and attention in chronic ambulatory traumatic brain injury: an exploratory study

    Patients with traumatic brain injury often have balance and attentive disorders. Video game therapy (VGT) has been proposed as a new intervention to improve mobility and attention through a reward-learning app...

    Sofia Straudi, Giacomo Severini, Amira Sabbagh Charabati, Claudia Pavarelli, Giulia Gamberini, Anna Scotti and Nino Basaglia

    BMC Neurology 2017 17:86

    Published on: 10 May 2017

  6. Research article

    Effect of tendon vibration during wide-pulse neuromuscular electrical stimulation (NMES) on the decline and recovery of muscle force

    Neuromuscular electrical stimulation (NMES) is commonly used to activate skeletal muscles and reverse muscle atrophy in clinical populations. Clinical recommendations for NMES suggest the use of short pulse wi...

    Vanesa Bochkezanian, Robert U. Newton, Gabriel S. Trajano, Amilton Vieira, Timothy S. Pulverenti and Anthony J. Blazevich

    BMC Neurology 2017 17:82

    Published on: 2 May 2017

  7. Research article

    Effectiveness of the capsaicin 8% patch in the management of peripheral neuropathic pain in European clinical practice: the ASCEND study

    In randomised studies, the capsaicin 8% patch has demonstrated effective pain relief in patients with peripheral neuropathic pain (PNP) arising from different aetiologies.

    Colette Mankowski, Chris D. Poole, Etienne Ernault, Roger Thomas, Ellen Berni, Craig J. Currie, Cecil Treadwell, José I. Calvo, Christina Plastira, Eirini Zafeiropoulou and Isaac Odeyemi

    BMC Neurology 2017 17:80

    Published on: 21 April 2017

  8. Case report

    Cortical laminar necrosis in dengue encephalitis—a case report

    Dengue encephalitis is a rare neurological manifestation of dengue fever. Its clinical presentation is similar to other viral encephalitides and encephalopathy. No single specific finding on magnetic resonance...

    Ravindra Kumar Garg, Imran Rizvi, Rajan Ingole, Amita Jain, Hardeep Singh Malhotra, Neeraj Kumar and Dhruv Batra

    BMC Neurology 2017 17:79

    Published on: 20 April 2017

  9. Case report

    Anti-MOG antibody-positive ADEM following infectious mononucleosis due to a primary EBV infection: a case report

    Anti-Myelin oligodendrocyte glycoprotein (MOG) antibodies are detected in various demyelinating diseases, such as pediatric acute disseminated encephalomyelitis (ADEM), recurrent optic neuritis, and aquaporin-...

    Yoshitsugu Nakamura, Hideto Nakajima, Hiroki Tani, Takafumi Hosokawa, Shimon Ishida, Fumiharu Kimura, Kimihiko Kaneko, Toshiyuki Takahashi and Ichiro Nakashima

    BMC Neurology 2017 17:76

    Published on: 19 April 2017

  10. Research article

    Clinical predictors for the prognosis of myasthenia gravis

    Clinical predictors for myasthenia gravis relapse and ocular myasthenia gravis secondary generalization during the first two years after disease onset remain incompletely identified. This study attempts to inv...

    Lili Wang, Yun Zhang and Maolin He

    BMC Neurology 2017 17:77

    Published on: 19 April 2017

  11. Case report

    An unusual delusion of duplication in a patient affected by Dementia with Lewy bodies

    Dementia with Lewy bodies (DLB) is the second most frequent diagnosis of progressive degenerative dementia in older people. Delusions are common features in DLB and, among them, Capgras syndrome represents the...

    Paolo Solla, Gioia Mura, Antonino Cannas, Gianluca Floris, Davide Fonti, Gianni Orofino, Mauro Giovanni Carta and Francesco Marrosu

    BMC Neurology 2017 17:78

    Published on: 19 April 2017

  12. Study protocol

    Study protocol: Insight 46 – a neuroscience sub-study of the MRC National Survey of Health and Development

    Increasing age is the biggest risk factor for dementia, of which Alzheimer’s disease is the commonest cause. The pathological changes underpinning Alzheimer’s disease are thought to develop at least a decade p...

    Christopher A. Lane, Thomas D. Parker, Dave M. Cash, Kirsty Macpherson, Elizabeth Donnachie, Heidi Murray-Smith, Anna Barnes, Suzie Barker, Daniel G. Beasley, Jose Bras, David Brown, Ninon Burgos, Michelle Byford, M. Jorge Cardoso, Ana Carvalho, Jessica Collins…

    BMC Neurology 2017 17:75

    Published on: 18 April 2017

  13. Technical advance

    A computerized tablet system for evaluating treatment of essential tremor by magnetic resonance guided focused ultrasound

    Transcranial magnetic resonance guided focused ultrasound is an emerging technology under evaluation for treatment of essential tremor, a prevalent movement disorder. A qualitative evaluation is performed by a...

    Fred Tam, Yuexi Huang, Michael L. Schwartz, Tom A. Schweizer, Kullervo Hynynen and Simon J. Graham

    BMC Neurology 2017 17:74

    Published on: 17 April 2017

  14. Commentary

    Big data and data repurposing - using existing data to answer new questions in vascular dementia research

    Traditional approaches to clinical research have, as yet, failed to provide effective treatments for vascular dementia (VaD). Novel approaches to collation and synthesis of data may allow for time and cost eff...

    Fergus N. Doubal, Myzoon Ali, G. David Batty, Andreas Charidimou, Maria Eriksdotter, Martin Hofmann-Apitius, Yun-Hee Kim, Deborah A. Levine, Gillian Mead, Hermann A. M. Mucke, Craig W. Ritchie, Charlotte J. Roberts, Tom C. Russ, Robert Stewart, William Whiteley and Terence J. Quinn

    BMC Neurology 2017 17:72

    Published on: 17 April 2017

  15. Research article

    Short-term motor learning through non-immersive virtual reality task in individuals with down syndrome

    Down syndrome (DS) has unique physical, motor and cognitive characteristics. Despite cognitive and motor difficulties, there is a possibility of intervention based on the knowledge of motor learning. However, ...

    Carlos Bandeira de Mello Monteiro, Talita Dias da Silva, Luiz Carlos de Abreu, Felipe Fregni, Luciano Vieira de Araujo, Fernando Henrique Inocêncio Borba Ferreira and Claudio Leone

    BMC Neurology 2017 17:71

    Published on: 14 April 2017

  16. Case report

    Double or nothing: red flag symptoms of critical carotid stenosis, a case report

    Detailed knowledge of every possible manifestation of Internal Carotid Artery (ICA) disease is important. For improving detection and a timely adoption of secondary prevention procedures or treatments. Transie...

    José Carlos Morán-Sánchez, Irene Gómez-Estévez, Yasmina El Berdei, José C. Gómez-Sánchez and María E. Ramos-Araque

    BMC Neurology 2017 17:69

    Published on: 5 April 2017

  17. Research article

    High dose vitamin D supplementation does not affect biochemical bone markers in multiple sclerosis – a randomized controlled trial

    People with multiple sclerosis have high risk of osteoporosis and fractures. A poor vitamin D status is a risk factor for MS, and vitamin D supplementation has been recommended both to prevent MS progression a...

    Trygve Holmøy, Jonas Christoffer Lindstrøm, Erik Fink Eriksen, Linn Hofsøy Steffensen and Margitta T. Kampman

    BMC Neurology 2017 17:67

    Published on: 4 April 2017

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