Table 2 Odds ratios, relative risks and corresponding 95% confidence intervals (CI) for pregabalin and gabapentin versus placebo, and for pregabalin versus gabapentin in the indirect comparison using placebo as the common comparator (base-case analysis using the ITT LOCF approach)

Pregabalin

150 mg vs. Placebo

2.75

1.73, 4.38

2.34

1.61, 3.27

300 mg vs. Placebo

4.62

3.16, 6.77

3.39

2.60, 4.29

450 mg vs. Placebo^b

6.26

4.33, 9.06

4.10

3.25, 5.02

600 mg vs. Placebo

7.77

5.32, 11.34

4.63

3.72, 5.58

Gabapentin

900 mg vs. Placebo

2.21

1.33, 3.68

1.97

1.29, 2.90

1200 mg vs. Placebo

2.54

1.64, 3.93

2.20

1.54, 3.04

1800 mg vs. Placebo

3.08

1.64, 5.81

2.55

1.54, 3.92

2400 mg vs. Placebo

3.54

1.48, 8.49

2.82

1.41, 4.85

Pregabalin vs. Gabapentin

150 mg vs. 900 mg

1.24

0.62, 2.48

1.21

0.64, 2.16

300 mg vs. 1200 mg

1.82

1.02, 3.25

1.68

1.02, 2.65

450 mg^a vs. 1800 mg

2.03

0.98, 4.23

1.84

0.98, 3.21

600 mg vs. 1800 mg

2.52

1.21, 5.27

2.19

1.19, 3.69

600 mg vs. 2400 mg^a

2.19

0.85, 5.69

1.96

0.86, 3.87