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Table 2 Cardiovascular Factors

From: Mood after stroke: a case control study of biochemical, neuro-imaging and socio-economic risk factors for major depression in stroke survivors

Variable

 

Depressed (n = 40)

 

Controls

(n = 87)

OR

(95% CI)*

p

Past medical history

n

%

n

%

  

Prior Stroke/TIA

16

40%

16

18%

3.0

(1.2 - 7.4)

0.015

Hypertension

30

75%

47

54%

2.6

(1.0 - 6.4)

0.03

Diabetes

5

13%

14

16%

0.7

0.8

Atrial Fibrillation

8

20%

14

16%

1.3

0.6

Myocardial Infarction

11

28%

23

26%

1.1

1.0

Angina

13

33%

21

24%

1.5

0.4

Peripheral Arterial Disease

9

23%

5

6%

4.8

(1.3 - 18)

0.01

Smoker/Ex-smoker

33

82%

55

63%

2.7

(1.0 - 7.7)

0.038

 

n

Mean ± SD

n

Mean ± SD

  

Alcohol (units/week)

40

10.2 ± 4.8

87

8.5 ± 4.5

 

0.6

Blood Pressure (mmHg)

      

Systolic

40

156 ± 22

87

147 ± 19

 

0.025

Diastolic

40

85 ± 12

87

80 ± 12

 

0.029

Mean Arterial Pressure

40

109 ± 14

87

102 ± 13

 

0.014

Pulse Pressure

40

71 ± 17

87

67 ± 16

 

0.22

Biochemistry

      

Uric Acid

40

0.39 ± 0.14

87

0.4 ± 0.2

 

0.8

Total Cholesterol mmol/l

40

5.2 ± 1.1

87

5.1 ± 1.1

 

0.5

LDL-C

40

2.8 ± 1

87

2.8 ± 0.8

 

0.7

HDL-C

40

1.4 ± 0.4

87

1.3 ± 0.3

 

0.15

  

Geometric Mean (95% CI)

 

Geometric Mean

(95% CI)

  

CRP†

37

5

(3.8-6.6)

76

4

(3.5-4.8)

 

0.2

Triglyceride†

37

1.9

(1.6-2.3)

82

2.0

(1.8-2.3)

 

0.8

Platelet Count†

37

267

(240-298)

77

246

(233-259)

 

0.12

Serum Homocysteine†

37

16.5

(14.5-18.8)

72

14.2

(13.1-15.4)

 

0.046

Serum Folic Acid†

37

4.7

(3.9-5.6)

73

5.9

(5.2-6.6)

 

0.03

  1. OR: Odds ratio for depressed vs.control; SD: Standard Deviation;
  2. LDL-C: low density lipoprotein cholesterol; HDL-C: high density lipoprotein cholesterol
  3. *95% CI: 95% Confidence Interval. Only shown where p < 0.1.
  4. †Logarithmic transform used (geometric means tested for significance).