Mood after stroke: a case control study of biochemical, neuro-imaging and socio-economic risk factors for major depression in stroke survivors

Table 3 Univariate analysis of CT abnormalities between depressed and controls

Variable	Depressed (n = 33)		Controls (n = 70)		OR (95% C.I)
	n	%	n	%	or p-value
Definite CT Abnormality present
Yes	30	91%	50	71%	4
No	3	9%	20	29%	(1 - 18)
Discrete Lesion seen (acute or chronic)
Yes	26	79%	38	54%	3.1
No	7	21%	32	46%	(1.1- 9.2)
Size of the Largest Lesion (acute or chronic)
< 1.5 cms	12	46%	8	21%	3.2
≥ 1.5 cms	14	54%	30	79%	(1.0 - 11.2)
Side of the Lesion (acute or chronic)
No Lesion	7	21%	32	46%
Right	14	42%	18	26%	P = 0.08
Left	9	27%	12	17%
Both Sides	3	9%	8	11%
Location of the Largest Lesion (acute or chronic):
Subcortical (including brainstem)	16	49%	20	29%
Cortical	10	30%	18	26%	p = 0.04
No Lesion	7	21%	32	46%
Cortical Atrophy:
Mild/Moderate	15	46%	30	43%	1.1
None	18	54%	40	57%	P = 0.8
Central Atrophy:
Mild/Moderate	13	39%	26	37%	1.1
None	20	61%	44	63%	P = 0.8
Lacunar Infarcts present
Yes	15	46%	20	29%	2.1
No	18	54%	50	71%	P = 0.1
White Matter Changes	n	Geometric Mean	n	Geometric Mean	p-value
Overall WMC score*	33	0.55	70	0.28	0.013
Basal Ganglia*		0.28		0.16	0.019
Frontal*		0.57		0.30	0.043
Parieto-occipital *		0.36		0.24	0.2

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