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Table 3 Univariate analysis of CT abnormalities between depressed and controls

From: Mood after stroke: a case control study of biochemical, neuro-imaging and socio-economic risk factors for major depression in stroke survivors

Variable Depressed
(n = 33)
Controls
(n = 70)
OR
(95% C.I)
  n % n % or p-value
Definite CT Abnormality present      
Yes 30 91% 50 71% 4
No 3 9% 20 29% (1 - 18)
Discrete Lesion seen
(acute or chronic)
     
Yes 26 79% 38 54% 3.1
No 7 21% 32 46% (1.1- 9.2)
Size of the Largest Lesion
(acute or chronic)
     
< 1.5 cms 12 46% 8 21% 3.2
≥ 1.5 cms 14 54% 30 79% (1.0 - 11.2)
Side of the Lesion
(acute or chronic)
     
No Lesion 7 21% 32 46%  
Right 14 42% 18 26% P = 0.08
Left 9 27% 12 17%  
Both Sides 3 9% 8 11%  
Location of the Largest Lesion (acute or chronic):      
Subcortical (including brainstem) 16 49% 20 29%  
Cortical 10 30% 18 26% p = 0.04
No Lesion 7 21% 32 46%  
Cortical Atrophy:      
Mild/Moderate 15 46% 30 43% 1.1
None 18 54% 40 57% P = 0.8
Central Atrophy:      
Mild/Moderate 13 39% 26 37% 1.1
None 20 61% 44 63% P = 0.8
Lacunar Infarcts present      
Yes 15 46% 20 29% 2.1
No 18 54% 50 71% P = 0.1
White Matter Changes n Geometric Mean n Geometric Mean p-value
Overall WMC score* 33 0.55 70 0.28 0.013
Basal Ganglia*   0.28   0.16 0.019
Frontal*   0.57   0.30 0.043
Parieto-occipital *   0.36   0.24 0.2
  1. OR: Odds ratio for depressed vs.control;
  2. 95% CI: 95% confidence interval. Only shown where p < 0.1.
  3. * Logarithmic transform used (geometric means tested for significance).