Microvessel changes after post-ischemic benign and malignant hyperemia: experimental study in rats

BMC Neurology

Table 2 Dynamic contrast enhanced perfusion MRI changes before and after reperfusion

Group	n	rCBV(%)	rMSI(%)
		mean ± SD	mean ± SD
Group 1
Before	8	86.0 ± 8.2*	110.6 ± 12.4
3 h	8	141.5 ± 22.3	80.7 ± 19.1
10 d	8	102.8 ± 11.3	109.0 ± 6.2**
Group 2
Before	14	46.2 ± 16.9*	69.7 ± 30.1
3 h	8	88.3 ± 13.8	74.8 ± 19.9
10 d	8	78.3 ± 9.3	75.0 ± 19.5
Group 3
Before	14	46.2 ± 16.9*	69.7 ± 30.1
3 h	6	127.8 ± 13.6	82.5 ± 30.7
10 d	6	173.5 ± 45.2	51.8 ± 10.9**
Group 4
Before	6	23.6 ± 16.8*	59.4 ± 27.5
3 h	6	103.4 ± 26.6	64.1 ± 28.9
10 d	6	80.0 ± 28.6	76.0 ± 24.3

rCBV = relative cerebral blood volume; rMSI = relative maximum slope of increase; before = before reperfusion; 3 h = three hours after reperfusion; 10 d = ten days after reperfusion.
*Significant difference (P < 0.5) among the different groups before reperfusion.
**Significant difference (P < 0.5) between group 1 and group 3 ten days after reperfusion.

ISSN: 1471-2377