Reference | Follow-up (months) | Anti-thyroid Abs (serum) | GD relapses | EAATD relapses | Other autoimmune manifestations | Treatment |
---|---|---|---|---|---|---|
Patient 1 [3] | 34 | - normal anti-TG, anti-TPO, and anti-TSH Receptor Abs | 1 relapse (month 18) | no | no | - prednisone (from month 1 to month 23) - RAI (month 20) - levothyroxine (from month 24) |
Patient 3 [14] | lost at follow-up | |||||
Patient 4 [15] | 48 | - normal anti-TG Abs - increased anti-TPO Abs | no | no | no | - prednisone (from month 1 to month 13) - propylthiouracil (from month 1 to month 4 and from month 18 to 40) - radioiodine therapy (month 6) - total thyroidectomy (month 32) |
Patient 5 [16] | 54 | - normal anti-TG, anti-TPO, and anti-TSH Receptor Abs | 1 relapse (month 20) | no | no | - prednisone (from month 1 to month 6) - propylthiouracil (from month 1 to month 18 and from month 20 to 45) - total thyroidectomy (month 45) - levothyroxine (from month 45) |
Patient 9 [19] | lost at follow-up | |||||
Patient 10 [20] | 33 | - normal anti-TG and anti-TSH Receptor Abs - increased anti-TPO Abs | no | 1 relapse (month 21) | autoimmune hemophilia (anti-factor VIII Abs +) | - levothyroxine (starting before EAATD occurrence) - prednisolone (from month 1) - cyclophosphamide (from month 24) |
Patient 12 [22] | 26 | - normal anti-TG Abs - increased anti-TPO and anti-TSH Receptor Abs | no | no | no | - methimazole (from month 1) |
Patient 14 [24] | 30 | - normal anti-TG Abs - increased anti-TPO and anti-TSH Receptor Abs | no | no | no | - methylprednisolone (month 1) - total thyroidectomy (month 1) - levothyroxine (from month 1) |