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Table 1 Cases of Holmes tremor in patients with AIDS and cerebral toxoplasmosis.

From: Cerebral toxoplasmosis in Acquired Immunodeficiency Syndrome (AIDS) patients also provides unifying pathophysiologic hypotheses for Holmes tremor

First author, Year of publication

Location of brain abscess

Involvement of the cerebello-thalamo-cortical and/or dento-rubro-olivary pathway

Involvement of the nigro-striatal pathway

Lekoubou A,

- Right posterior thalamus

- Internal capsule

Yes

No/hypothetical

Strecker K, 2006

   - Left midbrain

Yes

Yes

Pezzini A, 2002

- Left frontal superior gyrus,

- Inferior parietal lobule,

- right thalamus,

- right midbrain

Yes

Yes

Mattos JP, 2002

- Left midbrain

- Left cerebellar hemisphere

Yes

Yes

Micheli F, 1997

- Left posterior thalamus

- Posterior arm of internal capsule

Yes

No/Hypothetical

Koppel S, 1990

- Left midbrain

- Left frontal white matter

Yes

Yes

  1. Radio-clinical correlations and possible role of the cerebello-thalamo-cortical and/or dento-rubro-olivary and nigro-striatal pathways.