| |
Cerebral ischemic event
|
Cardiovascular ischemic event
|
Cerebral/cardiac ischemic events, or death of vascular/unknown cause
|
|---|
| |
HR
|
95% CI
|
HR
|
95% CI
|
HR
|
95% CI
|
|---|
|
3 < ABCD2 > 6
|
2.71
|
0.76-9.60
|
-*
|
-*
|
3.91
|
1.14-13.34
|
|
ABCD2 ≥6
|
2,61
|
0.62-10.93
|
-*
|
-*
|
4.26
|
1.13-16.08
|
|
Age ≥60 years
|
1.30
|
0.50-3.35
|
5.30
|
0.67-41.89
|
2.15
|
0.88-5.26
|
|
SBP ≥140 mmHg/DBP ≥90 mmHg
|
0.88
|
0.35-2.18
|
-*
|
-*
|
1.28
|
0.57-2.84
|
|
Unilateral weakness
|
4.14
|
0.96-17.92
|
1.80
|
0.20-16.10
|
3.37
|
1.00-11.30
|
|
Speech impairment only
|
1.39
|
0.20-9.90
|
8.68
|
0.96-78.42
|
2.62
|
0.66-10.47
|
|
Duration 10-59 min
|
1.32
|
0.37-4.70
|
1.83
|
0.30-10.97
|
1.63
|
0.53-4.99
|
|
Duration ≥60 min
|
0.80
|
0.25-2.50
|
0.64
|
0.12-3.48
|
1.00
|
0.37-2.72
|
|
Diabetes
|
1.46
|
0.49-4.33
|
4.94
|
1.41-17.30
|
1.83
|
0,79-4.26
|
|
Sex, female
|
1.13
|
0.49-2.62
|
0.93
|
0.23-3.76
|
1.18
|
0.56-2.45
|
|
Hypertension
|
0.99
|
0.39-2.51
|
-**
|
-**
|
1.20
|
0.54-2.68
|
|
Hypercholesterolemia
|
0.57
|
0.24-1.34
|
2.51
|
0.65-9.70
|
0.51
|
0.24-1.10
|
|
Body mass index
|
0.30
|
0.04-2.24
|
1.06
|
0.21-5.26
|
0.52
|
0.15-1.76
|
|
Nicotine abuse
|
1.30
|
0.57-2.94
|
0.99
|
0.27-3.69
|
1.06
|
0.53-2.12
|
|
Atrial fibrillation
|
0.94
|
0.28-3.17
|
-**
|
-**
|
1.02
|
0.35-2.93
|
|
Coronary artery disease
|
0.59
|
0.18-1.99
|
2.27
|
0.62-8.24
|
0.96
|
0.41-2.24
|
|
Heart failure
|
3.39
|
1.00-11.55
|
2.77
|
0.34-22.63
|
3.97
|
1.51-10.45
|
|
Peripheral artery disease
|
7.64
|
2.96-19.71
|
-**
|
-**
|
7.42
|
3.25-16.94
|
|
DWI abnormality
|
1.23
|
0.51-2.93
|
0.59
|
0.12-2.85
|
0.84
|
0.37-1.90
|
|
ECD: stenotic/occlusive
|
4.39
|
1.93-9.99
|
3.73
|
1.05-13.31
|
4.18
|
2.04-8.59
|
|
TCD: abnormal
|
4.99
|
1.97-12.62
|
9.62
|
2.46-37.68
|
5.13
|
2.26-11.67
|
- * Statistical analysis not possible owing to absence of events in one group.
- ** Statistical analysis not possible owing to small patient numbers.
- SBP: systolic blood pressure. DBP: diastolic blood pressure. ECD: extracranial Doppler and duplex ultrasonography. TCD: transcranial Doppler and duplex ultrasonography.
