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Table 1 Clinical background data of AUDS and MDE patients

From: Acute unstable depressive syndrome (AUDS) is associated more frequently with epilepsy than major depression

 

AUDS patients

(n = 16; age 32y ± 11; 6 males)

MDE patients

(n = 16; age 33y ± 13; 6 males)

P value*

Problematic alcohol consumption

4 (n = 15)

4 (n = 13)

ns

Alcohol withdrawal symptoms

0

3

ns

Drug abuse

1&

0

ns

Benzodiazepine medication

6

3

ns

Anti-epileptic medication for epilepsy #

4

0

ns

Anti-epileptic medication for other indications #

3

0

ns

Seizures in clinical history

6

0

0.018

Fulfilling clinical criteria for epilepsy

5

0

0.043

Focal or generalized slow, or epileptiform EEG activity (≥ 2 pathological features)

8

1

0.015

Cerebral MRI pathology

2 (n = 13)

2 (n = 13)

ns

Pathological findings at neurological bedside examination indicative of CNS pathology

3 (n = 11)

1 (n = 13)

ns

  1. The depicted data have been published elsewhere by our group. For further information on the data and the methods, see Vaaler AE et al. BMC Psychiatry. 2009; 9: 63 [25]. *Fisher exact tests. # Of a total of 7 patients, 3 were on lamotrigine, 3 on carbamazepine, 1 was on valproate. & Cannabis. AUDS: Acute Unstable Depressive Syndrome; MDE: Major Depressive Episode; ns: not significant.