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Table 1 Clinical follow-up of the MS case from MS onset (1999) up to January 2010. Abbreviations and symbols in the text (Case Presentation)

From: Treatment of refractory epilepsy with natalizumab in a patient with multiple sclerosis. Case report

Year 1999-2000 2001 2002 2003 2004 2005 2006 2007 2008 2009-2010
Non-epileptic MS relapses 1 0 1 0 1 0 0 1 1 0
Brain MRI activity
(new T2 or Gd + lesions or both)
+ - + - - n.d. - n.d. + -
EDSS score - 0 1 1 2 2 2.5* 3* 4** 2.5*
MS therapy - - GA GA GA GA GA GA GA Natalizumab
Partial seizures 1 (onset) 1 4 4 6 8 7 8 10 4
Generalized seizures 1 (onset) 1 3 2 3 6 5 5 7 0
Status epilepticus 0 0 0 0 0 1 0 1 1 0
AEDs (daily dose in mg)   VPA 600 VPA 1000 VPA 1000 VPA 1000 VPA 1300 VPA 1000 KEP 3000 KEP 3000 KEP 1000
    CBZ 300 CBZ 800 CBZ 1200 CBZ 1400 LMT§ OXC 2100 OXC 2400 GBP 900
        TOP 250   GBP 900