Table 4 Improvement in efficacy over a 2-year maintenance treatment with transdermal rotigotine: responder and remitter rates compared with baseline
End of year 1 | End of year 2 | |||
|---|---|---|---|---|
As observed (n = 217) | n = 295 | As observed (n = 190) | n = 220 | |
IRLS total score | ||||
Responder (≥50% improvement) | 75% | 68% | 65% | 79% |
Remitter (total score ≤10) | 60% | 54% | 53% | 62% |
Symptom-free (total score = 0) | 30% | 25% | 30% | 32% |
CGI-1 responder (≥50% improvement) | 79% | 72% | 75%a | 65% |
CGI-2 responder ('much' or 'very much' improved) | 97% | 89% | 95%a | 85% |