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Table 1 Demographic and clinical history data of patients with AD with higher (N = 463) and lower BPSD scores (N = 551).

From: Behavioural symptoms in patients with Alzheimer's disease and their association with cognitive impairment

 

AD + BPSD

AD - BPSD

Age (mean ± SD)

77.3 ± 6.7

77.1 ± 6.9

Gender (% men)

35.4%

34.8%

Years since AD symptoms (mean ± SD)

3.87 ± 2.32

3.89 ± 2.50

Years since AD diagnosis (mean ± SD)

1.32 ± 1.33

1.26 ± 1.19

Prior diagnosis of BPSD (before1 year)

42.7%

39.1%

Current treatment for AD

94.8%

95.6%

Behavioural symptoms (last year)

89.8%

89.7%

   Tearfulness

36.1%

40.8%

   Depression

49.9%

51.9%

   Concentration

59.0%

59.7%

   Cooperation

40.0%

42.5%

   Delusions

42.1%

37.0%

   Hallucinations

32.8%

28.5%

   Pacing

31.5%

26.5%

   Motor activity

35.2%

33.8%

   Appetite change

29.8%

29.6%

   Apathy

23.8%

24.0%

   Anxiety

27.6%

24.5%

   Agitation

25.5%

24.1%

   Delirium

8.9%

6.9%

Extrapyramidal symptoms (last year)

53.8%

54.6%

   Tremors

37.6%

38.3%

   Rigidity

14.0%

14.3%

   Hypokinesia

11.2%

9.8%

   Postural instability

9.9%

8.3%

   Fluctuating cognition

8.6%

7.6%

Psychotic breaks (last year)

18.4%

16.0%

   N° breaks (mean ± SD)

2.43 ± 3.58

1.74 ± 1.68

Dementia severity: MMSE Severe

12.8%

15.1%

Moderate

46.5%

46.6%

Mild

40.7%

38.3%

  1. AD + BPSD: patients with higher ADAS-Noncog scores. AD - BPSD: patients with lower ADAS-Noncog scores.