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Table 1 Demographic and clinical history data of patients with AD with higher (N = 463) and lower BPSD scores (N = 551).

From: Behavioural symptoms in patients with Alzheimer's disease and their association with cognitive impairment

  AD + BPSD AD - BPSD
Age (mean ± SD) 77.3 ± 6.7 77.1 ± 6.9
Gender (% men) 35.4% 34.8%
Years since AD symptoms (mean ± SD) 3.87 ± 2.32 3.89 ± 2.50
Years since AD diagnosis (mean ± SD) 1.32 ± 1.33 1.26 ± 1.19
Prior diagnosis of BPSD (before1 year) 42.7% 39.1%
Current treatment for AD 94.8% 95.6%
Behavioural symptoms (last year) 89.8% 89.7%
   Tearfulness 36.1% 40.8%
   Depression 49.9% 51.9%
   Concentration 59.0% 59.7%
   Cooperation 40.0% 42.5%
   Delusions 42.1% 37.0%
   Hallucinations 32.8% 28.5%
   Pacing 31.5% 26.5%
   Motor activity 35.2% 33.8%
   Appetite change 29.8% 29.6%
   Apathy 23.8% 24.0%
   Anxiety 27.6% 24.5%
   Agitation 25.5% 24.1%
   Delirium 8.9% 6.9%
Extrapyramidal symptoms (last year) 53.8% 54.6%
   Tremors 37.6% 38.3%
   Rigidity 14.0% 14.3%
   Hypokinesia 11.2% 9.8%
   Postural instability 9.9% 8.3%
   Fluctuating cognition 8.6% 7.6%
Psychotic breaks (last year) 18.4% 16.0%
   N° breaks (mean ± SD) 2.43 ± 3.58 1.74 ± 1.68
Dementia severity: MMSE Severe 12.8% 15.1%
Moderate 46.5% 46.6%
Mild 40.7% 38.3%
  1. AD + BPSD: patients with higher ADAS-Noncog scores. AD - BPSD: patients with lower ADAS-Noncog scores.