Patient-orientated longitudinal study of multiple sclerosis in south west England (The South West Impact of Multiple Sclerosis Project, SWIMS) 1: protocol and baseline characteristics of cohort

Table 1 Validated instruments included in questionnaire booklets

	MS Baseline Questionnaire	MS 6-Monthly Follow-Up Questionnaire Version A*	MS 6-Monthly Follow-Up Questionnaire Version B*	CIS Baseline Questionnaire	CIS 12-Monthly Follow-Up Questionnaire
EuroQol [27]	✓	✓		✓	✓
Fatigue Severity Scale [28]	✓	✓
Functional Assessment of MS (modified 44-items scale) [29]	✓		✓
General Health Questionnaire-30 [30]	✓	✓		✓	✓
Medical Outcomes Study Short Form 36-Item Health Study (version 2) [31]	✓		✓	✓	✓
MS Disease Impact Scale-29 (version 2) [7]	✓	✓
MS Neuropsychological Screening Questionnaire [32]	✓		✓
MS Walking Scale (version 2) [33]	✓	✓
Postal Barthel Index [34]	✓		✓

*To minimise the risk of overburdening participants, participants are randomly allocated to receive initially either Version A or Version B. Participants then receive alternate versions every six months.

ISSN: 1471-2377