Figure 1

Manhattan plots of the quantitative trait (CSF biomarkers: T-tau, P-tau _181P and Aβ _1-42 ) genome wide association analysis in normal subjects. Colors on x-axis indicate an autosomal chromosome (from chromosome 1 to chromosome 22). The y-axis indicates p-values (-log₁₀(observed p-values)). Red arrows indicate rs2899472 on chromosome 15 and blue arrow indicates rs1022442 on chromosome 21.