Change in "Pain Now" NPRS scores from pre-anesthetic time point during the treatment procedure. Values shown are mean and SEM. "Pain Now" NPRS scores decreased following topical anesthetic and increased following patch application in both treatment groups. Patients receiving NGX-4010 reported a mean maximum increase of 1.9 from the pre-anesthetic time point. NPRS scores did not increase above pre-procedure levels in those receiving control. NPRS scores in the NGX-4010 group decreased to below pre-procedure levels at 85 minutes after patch removal.