Figure 1

After preparation, cultivation for 14 days and baseline measurement, slices were traumatised by dropping of a stylus onto the CA ₁ region of the hippocampus. Figure 1a shows a native hippocampal slice prior to treatment. Figure 1b shows a non-traumatised, and un-treated negative control slice. The open circle tags the region of primary impact in Figure 1c and d. The treatment with 0.1 μM levosimendan (d) reduced visible the trauma intensity compared with the un-treated control (c).