Skip to main content

Table 1 Results of the evaluation of proteinase K digestion susceptibility.

From: A novel form of human disease with a protease-sensitive prion protein and heterozygosity methionine/valine at codon 129: Case report

Case

PK treatment

Mean

Std. deviation

Signal reduction (%)

P value

Proband

No

1.189

0.698

79.82

<0.0001

 

Yes

0.240

0.140

  

sCJD MM1

No

3.737

0.206

22.68

0.0041

 

Yes

2.890

1.076

  

MIE

No

0.062

0.009

4.37

0.2740

 

Yes

0.059

0.004

  

sCJD VV2

No

3.629

0.115

2.02

0.1133

 

Yes

3.556

0.152

  
  1. Proband: The case reported here; sCJD MM1: Sporadic Creutzfeldt-Jakob disease type 1 methionine homozygous at codon 129; sCJD VV2: Sporadic Creutzfeldt-Jakob disease type 2 valine homozygous at codon 129; MIE: A case of multi-infarct encephalopathy used as a negative control
Back to article page

BMC Neurology

ISSN: 1471-2377

Contact us