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Table 2 Patient characteristics and factors associated with impulse control and compulsive behaviours in patients with restless legs syndrome

From: Frequency of impulse control behaviours associated with dopaminergic therapy in restless legs syndrome

  

RLS + ICBs

RLSnonICBs

p-value

Total number

 

n = 10

n = 130

 

Female gender

 

n = 10 (100%)

n = 88 (67.6%)

0.04

Mean age of RLS onset in years (SD)

 

46.6 (10.1)

57 (15.9)

0.04

Medication

Dopaminergic

n = 10 (100%)

n = 122 (93.8%)

0.4

 

Other

n = 0 (0%)

n = 8 (6.2%)

 

Da type

Ropinirole

n = 3 (37.5%)

n = 29 (29.8%)

0.6

 

Pramipexole

n = 3 (37.5%)

n = 43 (44.3%)

0.5

 

Other

n = 2 (25%)

n = 25 (25.7%)

0.3

Mean DA dose as LEDD mg/d *(SD)

 

63.7 (52.7)

26.7 (26.4)

0.001

FHx alcohol use disorder

 

n = 3 (30%)

n = 12 (9.2%)

0.09

FHx gambling disorder

 

n = 2 (20%)

n = 2 (2%)

0.02

Hx experimental drug use

 

n = 5 (50%)

n = 10 (7.9%)

0.002

Cigarettes smoked daily

0

n = 5 (50%)

n = 81 (62.3%)

0.19

 

1-10

n = 0 (0%)

n = 10 (13%)

 
 

11-20

n = 3 (30%)

n = 13 (10%)

 
 

21-29

n = 0 (0%)

n = 6 (6%)

 
 

> 30

n = 2 (20%)

n = 10 (13%)

 

Alcohol daily glasses

0

n = 8 (80%)

n = 70/118 (59.3%)

0.18

 

1-7

n = 2 (20%)

n = 41/118 (34.8%)

 
 

8-14

n = 0 (0%)

n = 5/118 (4.2%)

 
 

15-21

n = 0 (0%)

n = 2/118 (1.7%)

 
 

> 22

n = 0 (0%)

n = 0 (0%)

 

Mean novelty seeking score (SD)

 

20.8 (5.3)

18 (5.5)

0.13

  1. *Calculation of Levodopa Daily Dose Equivalent (23); Abbreviations: RLS = Restless Legs Syndrome; ICBs = Impulse control behaviors; SD = standard deviation; DA = dopamine agonist; LEDD = levodopa dose equivalent; FHx = Family history; Hx = history; cut-off for significance: p < 0.05