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Table 2 Patient characteristics and factors associated with impulse control and compulsive behaviours in patients with restless legs syndrome

From: Frequency of impulse control behaviours associated with dopaminergic therapy in restless legs syndrome

   RLS + ICBs RLSnonICBs p-value
Total number   n = 10 n = 130  
Female gender   n = 10 (100%) n = 88 (67.6%) 0.04
Mean age of RLS onset in years (SD)   46.6 (10.1) 57 (15.9) 0.04
Medication Dopaminergic n = 10 (100%) n = 122 (93.8%) 0.4
  Other n = 0 (0%) n = 8 (6.2%)  
Da type Ropinirole n = 3 (37.5%) n = 29 (29.8%) 0.6
  Pramipexole n = 3 (37.5%) n = 43 (44.3%) 0.5
  Other n = 2 (25%) n = 25 (25.7%) 0.3
Mean DA dose as LEDD mg/d *(SD)   63.7 (52.7) 26.7 (26.4) 0.001
FHx alcohol use disorder   n = 3 (30%) n = 12 (9.2%) 0.09
FHx gambling disorder   n = 2 (20%) n = 2 (2%) 0.02
Hx experimental drug use   n = 5 (50%) n = 10 (7.9%) 0.002
Cigarettes smoked daily 0 n = 5 (50%) n = 81 (62.3%) 0.19
  1-10 n = 0 (0%) n = 10 (13%)  
  11-20 n = 3 (30%) n = 13 (10%)  
  21-29 n = 0 (0%) n = 6 (6%)  
  > 30 n = 2 (20%) n = 10 (13%)  
Alcohol daily glasses 0 n = 8 (80%) n = 70/118 (59.3%) 0.18
  1-7 n = 2 (20%) n = 41/118 (34.8%)  
  8-14 n = 0 (0%) n = 5/118 (4.2%)  
  15-21 n = 0 (0%) n = 2/118 (1.7%)  
  > 22 n = 0 (0%) n = 0 (0%)  
Mean novelty seeking score (SD)   20.8 (5.3) 18 (5.5) 0.13
  1. *Calculation of Levodopa Daily Dose Equivalent (23); Abbreviations: RLS = Restless Legs Syndrome; ICBs = Impulse control behaviors; SD = standard deviation; DA = dopamine agonist; LEDD = levodopa dose equivalent; FHx = Family history; Hx = history; cut-off for significance: p < 0.05