|
Characteristics
|
with ASCI (n = 7)
|
without ASCI (n = 30)
|
p-value
|
|---|
|
Median age; range (years)
|
71 (46-78)
|
55 (19-82)
|
0.033
*
|
|
Male
|
4
|
21
|
0.659
|
|
Female
|
3
|
9
| |
|
Underlying conditions
| | | |
|
Diabetes mellitus
|
3
|
2
|
0.037
*
|
|
Liver disease
|
3
|
3
|
0.068
|
|
Hypertension
|
1
|
6
|
1.000
|
|
Clinical manifestation
| | | |
|
Fever
|
5
|
15
|
0.113
|
|
Altered consciousness
|
7
|
15
|
0.028
*
|
|
Seizure
|
1
|
6
|
1.000
|
|
Previous stroke
|
2
|
0
|
0.032
*
|
|
Hydrocephalus
|
4
|
11
|
0.408
|
|
Positive CSF India ink staining
|
0
|
10/27
|
0.145
|
|
Positive CSF culture
|
4
|
20/28
|
0.652
|
|
CSF data median (range)*
| | | |
|
WBC count (10
9
/L)
|
144 (33-160)
|
136 (0-980)
|
0.575
|
|
Glucose level (mmol/L)
|
26.5 (14-53)
|
24 (0-255)
|
0.827
|
|
Glucose ratio
|
0.16 (0.07-0.31)
|
0.19 (0-0.96)
|
0.731
|
|
Total protein level (g/L)
|
232.5 (113-431)
|
106 (55-1626)
|
0.131
|
|
Lactate level (mmol/dL)
|
44.95 (31-67)
|
47.6 (9-97)
|
0.687
|
|
Cryptococcus antigen
|
1:384 (1:4-1:1024)
|
1:1024 (1:4-1:4096)
|
0.265
|
|
Prognosis
| | | |
|
Poor
|
7
|
11
|
0.003
|
- CSF = cerebrospinal fluid; WBC = white blood cell; * = p < 0.05
