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Table 2 Comparison of cryptococcal meningoencephalitis patients with and without acute/subacute cerebral infarction
| Characteristics | with ASCI (n = 7) | without ASCI (n = 30) | p-value |
|---|---|---|---|
| Median age; range (years) | 71 (46-78) | 55 (19-82) | 0.033 * |
| Male | 4 | 21 | 0.659 |
| Female | 3 | 9 | |
| Underlying conditions | |||
| Diabetes mellitus | 3 | 2 | 0.037 * |
| Liver disease | 3 | 3 | 0.068 |
| Hypertension | 1 | 6 | 1.000 |
| Clinical manifestation | |||
| Fever | 5 | 15 | 0.113 |
| Altered consciousness | 7 | 15 | 0.028 * |
| Seizure | 1 | 6 | 1.000 |
| Previous stroke | 2 | 0 | 0.032 * |
| Hydrocephalus | 4 | 11 | 0.408 |
| Positive CSF India ink staining | 0 | 10/27 | 0.145 |
| Positive CSF culture | 4 | 20/28 | 0.652 |
| CSF data median (range)* | |||
| WBC count (10 9 /L) | 144 (33-160) | 136 (0-980) | 0.575 |
| Glucose level (mmol/L) | 26.5 (14-53) | 24 (0-255) | 0.827 |
| Glucose ratio | 0.16 (0.07-0.31) | 0.19 (0-0.96) | 0.731 |
| Total protein level (g/L) | 232.5 (113-431) | 106 (55-1626) | 0.131 |
| Lactate level (mmol/dL) | 44.95 (31-67) | 47.6 (9-97) | 0.687 |
| Cryptococcus antigen | 1:384 (1:4-1:1024) | 1:1024 (1:4-1:4096) | 0.265 |
| Prognosis | |||
| Poor | 7 | 11 | 0.003 |
