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Table 6 The summary of non-CJD patients in the positive cases of ELISA of 14-3-3 γ protein

From: High sensitivity of an ELISA kit for detection of the gamma-isoform of 14-3-3 proteins: usefulness in laboratory diagnosis of human prion disease

Age

Sex

diagnosis

WB (14-3-3 protein)

ELISA

Real-time QUIC method

   

all isoforms

γ-specific isoform

γ-specific isoform

 

79

male

PCD/LEMS

+

+

4, 233

-

69

male

PCD/LEMS

+

+

4, 541

-

51

female

temporal epilepsy

+

+

3, 405

-

59

female

temporal epilepsy

+

+

3, 796

-

62

male

limbic encephalitis

+

+

3, 072

-

78

male

limbic encephalitis

+

+

5, 809

-

42

female

MELAS

+

+

4, 912

-

25

female

MELAS

+

+

5, 227

-

78

male

DAT

+

+

3, 110

-

62

female

DAT

+

+

3, 386

-

69

female

DAT

+

+

3, 892

-

57

male

DAT

+

-

3, 092

-

59

male

DAT

+

-

3, 074

-

61

male

DAT

+

-

3, 038

-

66

female

DAT

+

-

2, 941

-

67

female

DAT

-

-

2, 569

-

70

female

DAT

-

-

2, 534

-

78

female

DAT

-

-

2, 445

-

83

female

DAT

-

-

2, 410

-

89

female

DAT

-

-

2, 025

-

72

male

DAT

-

-

1, 949

-

59

female

DAT

-

-

1, 852

-

63

male

DAT

-

-

1, 709

-

  1. PCD: paraneoplastic cerebellar degeneration, LEMS: Lambert-Eaton myasthenic syndrome, MELAS: Mitochondrial myopathy, Encephalopathy, Lactic Acidosis, Stroke-like episodes, DAT: Dementia of Alzheimer's type