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Table 3 Presence and severity of CCSVI in multiple sclerosis patients and healthy controls.

From: Decreased brain venous vasculature visibility on susceptibility-weighted imaging venography in patients with multiple sclerosis is related to chronic cerebrospinal venous insufficiency

 

MS

(n = 59)

HC

(n = 33)

p

RR

(n = 41)

SP

(n = 18)

p

No CCSVI, n (%)

12 (21.3)

27 (81.8)

< .0001

11 (26.8)

1 (5.6)

NS

   CCSVI, n (%)

47 (79.7)

6 (18.2)

 

30 (73.2)

17 (94.4)

 

VHISS, mean (SD)

4.9 (3.1)

1.5 (1.6)

< .0001

5.2 (3.6)

4.2 (1.4)

NS

  1. CCSVI - chronic cerebrospinal venous insufficiency; VHISS - venous hemodynamic insufficiency score; MS - Multiple Sclerosis; HC - Healthy Controls; RR - Relapsing-Remitting; SP - Secondary Progressive; NS - non significant
  2. The differences between the study groups were tested using Fisher's exact tests and the Mann-Whitney rank sum test. All subjects had the 5 venous hemodynamic criteria correctly assessed.