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Table 1 Classification, demographics, clinical characteristics and treatment of patients with idiopathic inflammatory myopathies

From: Clinical characteristics and favorable long-term outcomes for patients with idiopathic inflammatory myopathies: a retrospective single center study in China

  All PM DM ADM OM JM P value
No. of patients no(%) 188 41(21.8) 100(53.2) 13(6.9) 27(14.4) 7(3.7)  
Died 32 5 20 4 2 1 NA
Mortality (%) 17.0 11.9 20 30.8 7.69 14.3 NA
Male: female ratio 1:2.1 1:2.4 1:1.8 1:1.6 1:8 1:0.4 NA
Mean age ± S.D at onset (y) 43.8(15.8) 44.9(15.0) 44.9(14.9) 50 (13.8) 42(16.8) 15.7(2) < 0.001†
Complicated with ILD, n, % 92(48.9) 17(40.5) 49(49.0) 13(100.0) 11(42.3) 2(28.6) 0.003
Complicated with PAH, n, % 20(10.6) 7(16.7) 7(7.0) 0(0.0) 6(23.1) 0(0.0) > 0.05
Complicated with malignancy, n, % 11(5.9) 1(2.4) 10(10.0) 0(0.0) 0(0.0) 0(0.0) > 0.05
Complicated with oropharyngeal dysphagia, n, % 75(39.9) 14(33.3) 36(36.0) 5(38.5) 15(57.7) 5(71.4) > 0.05
Cardiac involvement, n, % 64(34.0) 14(33.3) 37(37.0) 4(30.8) 4(15.4) 5(71.4) > 0.05
Mechanic hand at anytime, n, % 28(14.9) 1(2.4) 21(21.0) 3(23.1) 3(11.5) 0(0.0) 0.038
Raynaud phenomenon at anytime, n, % 29(15.4) 5(11.9) 10(10.0) 3(23.1) 11(42.3) 0(0.0) 0.001
Creatine kinase at initial visit in our center, mean (IQR) 1440.9
(83, 1561.8)
2106.8
(594.5, 2577.5)
1117.4
(68.3, 971.3)
67.9
(35, 93.5)
1867.9
(236, 2452)
3065.4
(114, 7908)
0.013††
  1. † indicates that the comparison between PM, DM, ADM, OM, vs JM (p < 0.001), but the comparison among PM, DM, ADM and OM were no significant.
  2. ††indicates that the comparison between PM vs DM (p < 0.05), PM vs ADM (p < 0.01), DM vs JM (p < 0.05), ADM vs OM (p < 0.05), ADM vs JM (p < 0.01).
  3. PM: polymyositis; DM: dermatomyositis; ADM: amyopathic dermatomyositis; OM: overlap myositis; JM: juvenile polymyositis or dermatomyositis; ILD: interstitial lung disease; PAH: pulmonary arterial hypertension; IQR: interquartile range; NA: not assessment.