Skip to main content

Table 3 Frequency of damage in the IIM patients at the end of the follow-up using the Myositis Damage Index (MDI)

From: Clinical characteristics and favorable long-term outcomes for patients with idiopathic inflammatory myopathies: a retrospective single center study in China

Damage item Survival IIM patients‡, n = 156, (%)
Muscle severity, VAS 31(20.0)
   Muscle atrophy 7(4.7)
   Weakness 53(34.0)
   Muscle dysfunction 10(6.7)
Skeletal severity, VAS, no of test(149)# 44(29.4)
   Joint contracture 1(0.7)
   Osteopososis with fracture 4(2.8)
   Avascular necrosis 5(3.5)
   Arthropathy 9(6.3)
Cutaneous severity, VAS 31(20.0)
   Calcinosis 7(4.7)
   Alopecia 2(1.3)
   Cutaneous scarring 15(9.3)
   Poikiloderma 20(12.7)
   Lipodystrophy 4(2.6)
Gastrointestinal severity, VAS 8(5.3)
   Dysphagia 8(5.3)
   Gastrointestinal dysmotility 1(0.7)
   Gastrointestinal infarction 1(0.7)
Pulmonary severity, VAS 77(49.3)
   Dysphonia 11(7.1)
   Impaired lung function 75(48.1)
   Pulmonary fibrosis 75(48.1)
   Pulmonary hypertension 20(12.8)
Cardiovascular severity, VAS 27(17.3)
   Hypertension 26(16.7)
   Ventricular dysfunction 2(1.3)
   Angina 3(1.9)
   Myocardial infarction 3(1.9)
Peripheral vascular severity, VAS 2(1.3)
   Tissue pulp loss 0(0.0)
   Digit loss 2(1.3)
   Thrombosis 0(0.0)
   Claudication 0(0.0)
Endocrine severity, VAS 41(26.3)
   Growth failure 0(0)
   Delay in secondary sexual characteristics 0(0)
   Hirsutism 0(0.0)
   Irregular menses 2(1.3)
   Amenorrhea 0(0.0)
   Diabetes 41(26.3)
   Infertility NA
   Sexual dysfunction NA
Ocular severity, VAS 4(2.7)
   Cataract 2(1.3)
   Vision loss 1(0.6)
Infection severity, VAS 4(2.6)
   Chronic infection 3(2.0)
   Multiple infections 1(0.6)
Malignancy severity, VAS 4(2.6)
   Malignancy 4(2.6)
Total damage  
   Total MDI severity of damage > 0† 112(71.8)
   Total MDI extent of damage > 0‡ 115(73.7)
  1. #indicates the number after excluded the patients complicated with rheumatoid arthritis (n = 7) NA: not applicable. VAS, visual analogue scale.
  2. † Severity of damage was assessed in 9 organ systems and 2 categories of illness (infection and malignancy) and summed to provide a total MDI severity of damage score.
  3. ‡ Individual damage items were assessed in each organ system and category of illness and summed to provide a total MDI extent of damage score.