Cognitive function and quality of life in multiple sclerosis patients: a cross-sectional study

Baumstarck-Barrau, Karine; Simeoni, Marie-Claude; Reuter, Françoise; Klemina, Irina; Aghababian, Valérie; Pelletier, Jean; Auquier, Pascal

doi:10.1186/1471-2377-11-17

BMC Neurology

Table 4 Predictive factors for MusiQoL dimensions and index: multivariate analysis (standardised beta coefficient)

From: Cognitive function and quality of life in multiple sclerosis patients: a cross-sectional study

		ADL^a	PWB^a	RFr^a	SPT^a	RFa^a	RHCS^a	SSL^a	COP^a	REJ^a	Index
Gender (0 women, 1 men)	β*	-0.011	0.161	-0.563	-0.017	-0.036	-0.302	-0.416	0.329	0.285	0.026
	p*	0.938	0.314	0.004	0.922	0.837	0.052	0.037	0.057	0.158	0.886
Marital status (0 single, 1 couple)	β*	-0.077	-0.015	0.421	0.075	0.459	0.722	0.261	-0.011	-0.013	0.526
	p*	0.571	0.919	0.02	0.642	0.008	<10-3	0.130	0.944	0.945	0.007
CIS^b (0 PP^b)	β*	-0.312	-0.461	-0.106	-0.226	-0.087	-0.461	0.070	-0.345	-0.284	-0.309
	p*	0.092	0.027	0.644	0.297	0.690	0.019	0.738	0.107	0.250	0.124
SP^b (0 PP^b)	β*	-0.013	-0.049	0.392	-0.158	0.182	-0.130	0.416	-0.112	0.135	0.127
	p*	0.946	0.821	0.138	0.507	0.449	0.534	0.177	0.631	0.620	0.670
RR^b (0 PP^b)	β*	-0.389	-0.415	-0.037	-0.369	0.025	-0.654	0.285	-0.500	-0.271	-0.418
	p*	0.067	0.077	0.890	0.140	0.922	0.004	0.317	0.043	0.325	0.117
Age	β*	0.159	0.285	-0.368	0.363	-0.171	-0.045	-0.295	0.357	-0.004	-0.260
	p*	0.246	0.064	0.056	0.030	0.299	0.750	0.105	0.029	0.980	0.132
EDSS^c	β*	-0.421	0.429	0.214	0.171	0.274	0.575	0.401	0.376	0.332	0.633
	p*	0.027	0.038	0.360	0.436	0.214	0.005	0.084	0.085	0.190	0.006
Disease duration	β*	0.361	-0.021	0.135	-0.071	-0.203	-0.360	-0.185	0.085	0.295	-0.182
	p*	0.044	0.908	0.565	0.731	0.338	0.054	0.449	0.674	0.209	0.434
MFIS-To^d	β*	-0.324	-0.272	0.187	-0.680	0.113	0.373	-0.085	-0.023	-0.061	0.130
	p*	0.043	0.117	0.353	0.001	0.550	0.027	0.670	0.896	0.770	0.493
BDI^e	β*	-0.142	-0.317	-0.115	0.318	-0.317	-0.116	-0.061	-0.343	-0.200	-0.413
	p*	0.323	0.046	0.530	0.068	0.072	0.438	0.728	0.044	0.304	0.018
SRT-L^f	β*	-0.259	0.155	-0.433	-0.071	-0.194	-0.140	-0.456	0.071	0.202	-0.228
	p*	0.152	0.431	0.069	0.739	0.343	0.452	0.068	0.732	0.401	0.276
SRT-D^f	β*	0.121	-0.075	-0.171	0.181	-0.009	-0.210	0.155	0.133	-0.208	0.035
	p*	0.482	0.692	0.439	0.378	0.965	0.246	0.518	0.507	0.366	0.864
SPART-T^f	β*	0.014	0.184	-0.086	0.034	-0.005	-0.429	0.004	0.307	0.120	-0.152
	p*	0.928	0.270	0.667	0.852	0.977	0.010	0.983	0.087	0.552	0.413
WLG^f	β*	0.244	0.072	0.196	0.220	-0.167	-0.100	0.392	-0.042	-0.023	0.078
	p*	0.084	0.640	0.301	0.186	0.312	0.489	0.056	0.795	0.902	0.666

^aADL activity of daily living, PWB psychological well-being, RFr relationships with friends, SPT symptoms, RFa relationships with family, RHCS relationships with health care system, SSL sentimental and sexual life, COP coping, REJ rejection
^bRR Relapsing remitting, PP Primary progressive, SP Secondary progressive, CIS Clinically isolated syndrome
^cEDSS Expanded Disability Status Scale
^dMFIS-To Modified Fatigue Impact Scale total
^eBDI Beck Depression Inventory
^fSRT-L Selective Reminding Test Long-term, SRT-D Selective Reminding Test Delayed, SPART-T SPAtial Recall Test Total, WLG Word List Generation test
*β: standardised beta coefficient (β represents the change of the standard deviation in QoL score resulting from a change of one standard deviation in the independent variable); p: p-value
Bold values: p < 0.05

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ISSN: 1471-2377

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