TY - STD TI - Alzheimer's Association: 2010 Alzheimer's disease facts and figures. Alzheimer's Association web site. Accessed September 22, 2010, [http://www.alz.org/documents_custom/report_alzfactsfigures2010.pdf] UR - http://www.alz.org/documents_custom/report_alzfactsfigures2010.pdf ID - ref1 ER - TY - JOUR AU - Hebert, L. E. AU - Scherr, P. A. AU - Bienias, J. L. AU - Bennett, D. A. AU - Evans, D. A. PY - 2003 DA - 2003// TI - Alzheimer disease in the US population: prevalence estimates using the 2000 census JO - Arch Neurol VL - 60 UR - https://doi.org/10.1001/archneur.60.8.1119 DO - 10.1001/archneur.60.8.1119 ID - Hebert2003 ER - TY - STD TI - Aricept [package insert]. 2006, Teaneck, NJ: Eisai Inc ID - ref3 ER - TY - STD TI - Namenda [package insert]. 2007, St. Louis, MO: Forest Laboratories Inc ID - ref4 ER - TY - JOUR AU - Perry, E. K. AU - Tomlinson, B. E. AU - Blessed, G. AU - Bergmann, K. AU - Gibson, P. H. AU - Perry, R. H. PY - 1978 DA - 1978// TI - Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia JO - Br Med J VL - 2 UR - https://doi.org/10.1136/bmj.2.6150.1457 DO - 10.1136/bmj.2.6150.1457 ID - Perry1978 ER - TY - JOUR AU - Herholz, K. AU - Carter, S. F. AU - Jones, M. PY - 2007 DA - 2007// TI - Positron emission tomography imaging in dementia JO - Br J Radiol VL - 80 UR - https://doi.org/10.1259/bjr/97295129 DO - 10.1259/bjr/97295129 ID - Herholz2007 ER - TY - JOUR AU - Iyo, M. AU - Namba, H. AU - Fukushi, K. AU - Shinotoh, H. AU - Nagatsuka, S. AU - Suhara, T. AU - Sudo, Y. AU - Suzuki, K. AU - Irie, T. PY - 1997 DA - 1997// TI - Measurement of acetylcholinesterase by positron emission tomography in the brains of healthy controls and patients with Alzheimer's disease JO - Lancet VL - 349 UR - https://doi.org/10.1016/S0140-6736(96)09124-6 DO - 10.1016/S0140-6736(96)09124-6 ID - Iyo1997 ER - TY - JOUR AU - Kuhl, D. E. AU - Minoshima, S. AU - Frey, K. A. AU - Foster, N. L. AU - Kilbourn, M. R. AU - Koeppe, R. A. PY - 2000 DA - 2000// TI - Limited donepezil inhibition of acetylcholinesterase measured with positron emission tomography in living Alzheimer cerebral cortex JO - Ann Neurol VL - 48 UR - https://doi.org/3.0.CO;2-H DO - 3.0.CO;2-H ID - Kuhl2000 ER - TY - JOUR AU - Bohnen, N. I. AU - Kaufer, D. I. AU - Hendrickson, R. AU - Ivanco, L. S. AU - Lopresti, B. AU - Davis, J. G. AU - Constantine, G. AU - Mathis, C. A. AU - Moore, R. Y. AU - DeKosky, S. T. PY - 2005 DA - 2005// TI - Cognitive correlates of alterations in acetylcholinesterase in Alzheimer's disease JO - Neurosci Lett VL - 380 UR - https://doi.org/10.1016/j.neulet.2005.01.031 DO - 10.1016/j.neulet.2005.01.031 ID - Bohnen2005 ER - TY - JOUR AU - Hanyu, H. AU - Asano, T. AU - Sakurai, H. AU - Tanaka, Y. AU - Takasaki, M. AU - Abe, K. PY - 2002 DA - 2002// TI - MR analysis of the substantia innominata in normal aging, Alzheimer disease, and other types of dementia JO - AJNR Am J Neuroradiol VL - 23 ID - Hanyu2002 ER - TY - JOUR AU - Teipel, S. J. AU - Flatz, W. H. AU - Heinsen, H. AU - Bokde, A. L. AU - Schoenberg, S. O. AU - Stockel, S. AU - Dietrich, O. AU - Reiser, M. F. AU - Moller, H. J. AU - Hampel, H. PY - 2005 DA - 2005// TI - Measurement of basal forebrain atrophy in Alzheimer's disease using MRI JO - Brain VL - 128 UR - https://doi.org/10.1093/brain/awh589 DO - 10.1093/brain/awh589 ID - Teipel2005 ER - TY - JOUR AU - Lahiri, D. K. AU - Rogers, J. T. AU - Greig, N. H. AU - Sambamurti, K. PY - 2004 DA - 2004// TI - Rationale for the development of cholinesterase inhibitors as anti-Alzheimer agents JO - Curr Pharm Des VL - 10 UR - https://doi.org/10.2174/1381612043383331 DO - 10.2174/1381612043383331 ID - Lahiri2004 ER - TY - JOUR AU - Whitehouse, P. J. PY - 1998 DA - 1998// TI - The cholinergic deficit in Alzheimer's disease JO - J Clin Psychiatry VL - 59 ID - Whitehouse1998 ER - TY - JOUR AU - Davis, K. L. AU - Mohs, R. C. AU - Marin, D. AU - Purohit, D. P. AU - Perl, D. P. AU - Lantz, M. AU - Austin, G. AU - Haroutunian, V. PY - 1999 DA - 1999// TI - Cholinergic markers in elderly patients with early signs of Alzheimer disease JO - JAMA VL - 281 UR - https://doi.org/10.1001/jama.281.15.1401 DO - 10.1001/jama.281.15.1401 ID - Davis1999 ER - TY - JOUR AU - Sramek, J. J. AU - Cutler, N. R. PY - 2000 DA - 2000// TI - RBC cholinesterase inhibition: a useful surrogate marker for cholinesterase inhibitor activity in Alzheimer disease therapy? JO - Alzheimer Dis Assoc Disord VL - 14 UR - https://doi.org/10.1097/00002093-200010000-00006 DO - 10.1097/00002093-200010000-00006 ID - Sramek2000 ER - TY - JOUR AU - Jann, M. W. AU - Shirley, K. L. AU - Small, G. W. PY - 2002 DA - 2002// TI - Clinical pharmacokinetics and pharmacodynamics of cholinesterase inhibitors JO - Clin Pharmacokinet VL - 41 UR - https://doi.org/10.2165/00003088-200241100-00003 DO - 10.2165/00003088-200241100-00003 ID - Jann2002 ER - TY - JOUR AU - Kaasinen, V. AU - Nagren, K. AU - Jarvenpaa, T. AU - Roivainen, A. AU - Yu, M. AU - Oikonen, V. AU - Kurki, T. AU - Rinne, J. O. PY - 2002 DA - 2002// TI - Regional effects of donepezil and rivastigmine on cortical acetylcholinesterase activity in Alzheimer's disease JO - J Clin Psychopharmacol VL - 22 UR - https://doi.org/10.1097/00004714-200212000-00012 DO - 10.1097/00004714-200212000-00012 ID - Kaasinen2002 ER - TY - JOUR AU - Homma, A. AU - Imai, Y. AU - Tago, H. AU - Asada, T. AU - Shigeta, M. AU - Iwamoto, T. AU - Takita, M. AU - Arimoto, I. AU - Koma, H. AU - Ohbayashi, T. PY - 2008 DA - 2008// TI - Donepezil treatment of patients with severe Alzheimer's disease in a Japanese population: results from a 24-week, double-blind, placebo-controlled, randomized trial JO - Dement Geriatr Cogn Disord VL - 25 UR - https://doi.org/10.1159/000122961 DO - 10.1159/000122961 ID - Homma2008 ER - TY - JOUR AU - Whitehead, A. AU - Perdomo, C. AU - Pratt, R. D. AU - Birks, J. AU - Wilcock, G. K. AU - Evans, J. G. PY - 2004 DA - 2004// TI - Donepezil for the symptomatic treatment of patients with mild to moderate Alzheimer's disease: a meta-analysis of individual patient data from randomised controlled trials JO - Int J Geriatr Psychiatry VL - 19 UR - https://doi.org/10.1002/gps.1133 DO - 10.1002/gps.1133 ID - Whitehead2004 ER - TY - JOUR AU - Nozawa, M. AU - Ichimiya, Y. AU - Nozawa, E. AU - Utumi, Y. AU - Sugiyama, H. AU - Murayama, N. AU - Iseki, E. AU - Arai, H. PY - 2009 DA - 2009// TI - Clinical effects of high oral dose of donepezil for patients with Alzheimer's disease in Japan JO - Psychogeriatrics VL - 9 UR - https://doi.org/10.1111/j.1479-8301.2009.00291.x DO - 10.1111/j.1479-8301.2009.00291.x ID - Nozawa2009 ER - TY - JOUR AU - Burns, A. AU - Rossor, M. AU - Hecker, J. AU - Gauthier, S. AU - Petit, H. AU - Moller, H. J. AU - Rogers, S. L. AU - Friedhoff, L. T. PY - 1999 DA - 1999// TI - The effects of donepezil in Alzheimer's disease - results from a multinational trial JO - Dement Geriatr Cogn Disord VL - 10 UR - https://doi.org/10.1159/000017126 DO - 10.1159/000017126 ID - Burns1999 ER - TY - JOUR AU - Rogers, S. L. AU - Doody, R. S. AU - Mohs, R. C. AU - Friedhoff, L. T. PY - 1998 DA - 1998// TI - Donepezil improves cognition and global function in Alzheimer disease: a 15-week, double-blind, placebo-controlled study JO - Arch Intern Med VL - 158 UR - https://doi.org/10.1001/archinte.158.9.1021 DO - 10.1001/archinte.158.9.1021 ID - Rogers1998 ER - TY - JOUR AU - Rogers, S. L. AU - Farlow, M. R. AU - Doody, R. S. AU - Mohs, R. AU - Friedhoff, L. T. PY - 1998 DA - 1998// TI - A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease JO - Neurology VL - 50 UR - https://doi.org/10.1212/WNL.50.1.136 DO - 10.1212/WNL.50.1.136 ID - Rogers1998 ER - TY - JOUR AU - Doody, R. S. AU - Corey-Bloom, J. AU - Zhang, R. AU - Li, H. AU - Ieni, J. AU - Schindler, R. PY - 2008 DA - 2008// TI - Safety and tolerability of donepezil at doses up to 20 mg/day: results from a pilot study in patients with Alzheimer's disease JO - Drugs Aging VL - 25 UR - https://doi.org/10.2165/00002512-200825020-00008 DO - 10.2165/00002512-200825020-00008 ID - Doody2008 ER - TY - JOUR AU - Farlow, M. R. AU - Salloway, S. AU - Tariot, P. N. AU - Yardley, J. AU - Moline, M. L. AU - Wang, Q. AU - Brand-Schieber, E. AU - Zou, H. AU - Hsu, T. AU - Satlin, A. PY - 2010 DA - 2010// TI - Effectiveness and tolerability of high-dose (23 mg/d) versus standard-dose (10 mg/d) donepezil in moderate to severe Alzheimer's disease: a 24-week, randomized, double-blind study JO - Clin Ther VL - 32 UR - https://doi.org/10.1016/j.clinthera.2010.06.019 DO - 10.1016/j.clinthera.2010.06.019 ID - Farlow2010 ER - TY - STD TI - The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2377/11/21/prepub UR - http://www.biomedcentral.com/1471-2377/11/21/prepub ID - ref26 ER -