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Table 2 MOS-SF-36 Quality of Life Domains for Cohorts 1 and 2 (mean [95% confidence intervals]; probability).

From: Migraine headaches in Chronic Fatigue Syndrome (CFS): Comparison of two prospective cross-sectional studies

  Cohort 1 Cohort 2
Domain HC n = 295 CFS * n = 145 HC n = 19 CFS ** n = 49 CFS+MO** n = 28 CFS+MA** n = 12 CFS+T ** n = 9
Physical Functioning 71.6 [67.8-75.4] 47.6 [43.4-52.1] p < 10-10 91.1 [82.4-99.7] 41.4 [34.6-48.2] p < 10-10 43.7 [35.5-51.9] p = 10-9 28.8 [15.6-41.9] p = 10-8 51.7 [34.5-68.8] p = 0.0001
Social Functioning 67.4 [63.2-71.6] 46.4 [41.8-51.0] p = 10-9 87.5 [76.5-98.5] 26.9 [21.0-32.8] p < 10-10 25.5 [17.9-33.0] p < 10-10 23.9 [9.3-38.4] p = 10-7 35.9 [26.2-45.7] P = 0.000005
Role-Physical 60.5 [63.2-71.6] 18.5 [13.3-23.7] p < 10-10 76.3 [57.8-94.9] 5.6 [0.8-10.4] p < 10-10 8.0 [0.5-15.6] p = 10-9 4.2 [-4.0-12.3] p = 10-6 0 P = 0.000009
Role-Emotional 71.6 [62.8-80.3] 53.3 [46.2-60.5] p = 0.008 86.0 [72.5-99.5] 57.6 [44.8-70.5] 59.3 [42.0-76.5] p = 0.03 55.6 [28.5-82.7] p = 0.04 55.6 [24.8-86.4] p = 0.048
Mental Health 66.8 [63.0-70.5] 58.4 [54.9-61.9] p = 0.006 79.2 [74.0-84.3] 62.6 [57.0-68.3] 64.9 [57.9-71.8] p = 0.005 59.7 [45.1-74.2] p = 0.007 59.6 [48.1-71.0] p = 0.001
Vitality 50.1 [47.1-53.1] 25.4 [22.3-28.5] p < 10-10 66.1 [56.5-75.8] 13.9 [10.5-17.2] p < 10-10 14.8 [10.3-19.3] p < 10-10 6.7 [2.1-11.2] p = 10-10 20.6 [12.6-28.5] p = 10-6
Bodily Pain 60.5 [56.5-64.6] 35.1 [31.4-38.8] p < 10-10 83.8 [72.4-95.2] 34.1 [28.1-40.2] p < 10-10 32.8 [25.3-40.3] p = 10-9 30.6 [16.2-44.9] p = 10-6 42.8 [29.5-56.0] p = 0.0003
General Health 64.5 [56.5-64.6] 38.3 [34.3-42.3] p < 10-10 76.8 [69.5-84.2] 33.0 [27.8-38.2] p < 10-10 36.2 [28.3-44.1] p = 10-8 28.8 [19.9-37.6] p = 10-8 29.1 [20.9-37.4] p = 10-8
  1. 2-tailed unpaired Student's t-tests with Bonferroni corrections following ANOVA (p < 0.05): * vs. HC of Cohort 1 and ** vs. HC of Cohort 2.