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Table 2 MOS-SF-36 Quality of Life Domains for Cohorts 1 and 2 (mean [95% confidence intervals]; probability).

From: Migraine headaches in Chronic Fatigue Syndrome (CFS): Comparison of two prospective cross-sectional studies

  Cohort 1 Cohort 2
Domain HC
n = 295
CFS *
n = 145
HC
n = 19
CFS **
n = 49
CFS+MO**
n = 28
CFS+MA**
n = 12
CFS+T **
n = 9
Physical Functioning 71.6
[67.8-75.4]
47.6
[43.4-52.1]
p < 10-10
91.1
[82.4-99.7]
41.4
[34.6-48.2]
p < 10-10
43.7
[35.5-51.9]
p = 10-9
28.8
[15.6-41.9]
p = 10-8
51.7
[34.5-68.8]
p = 0.0001
Social Functioning 67.4
[63.2-71.6]
46.4
[41.8-51.0]
p = 10-9
87.5
[76.5-98.5]
26.9
[21.0-32.8]
p < 10-10
25.5
[17.9-33.0]
p < 10-10
23.9
[9.3-38.4]
p = 10-7
35.9
[26.2-45.7]
P = 0.000005
Role-Physical 60.5
[63.2-71.6]
18.5
[13.3-23.7]
p < 10-10
76.3
[57.8-94.9]
5.6
[0.8-10.4]
p < 10-10
8.0
[0.5-15.6]
p = 10-9
4.2
[-4.0-12.3]
p = 10-6
0
P = 0.000009
Role-Emotional 71.6
[62.8-80.3]
53.3
[46.2-60.5]
p = 0.008
86.0
[72.5-99.5]
57.6
[44.8-70.5]
59.3
[42.0-76.5]
p = 0.03
55.6
[28.5-82.7]
p = 0.04
55.6
[24.8-86.4]
p = 0.048
Mental Health 66.8
[63.0-70.5]
58.4
[54.9-61.9]
p = 0.006
79.2
[74.0-84.3]
62.6
[57.0-68.3]
64.9
[57.9-71.8]
p = 0.005
59.7
[45.1-74.2]
p = 0.007
59.6
[48.1-71.0]
p = 0.001
Vitality 50.1
[47.1-53.1]
25.4
[22.3-28.5]
p < 10-10
66.1
[56.5-75.8]
13.9
[10.5-17.2]
p < 10-10
14.8
[10.3-19.3]
p < 10-10
6.7
[2.1-11.2]
p = 10-10
20.6
[12.6-28.5]
p = 10-6
Bodily Pain 60.5
[56.5-64.6]
35.1
[31.4-38.8]
p < 10-10
83.8
[72.4-95.2]
34.1
[28.1-40.2]
p < 10-10
32.8
[25.3-40.3]
p = 10-9
30.6
[16.2-44.9]
p = 10-6
42.8
[29.5-56.0]
p = 0.0003
General Health 64.5
[56.5-64.6]
38.3
[34.3-42.3]
p < 10-10
76.8
[69.5-84.2]
33.0
[27.8-38.2]
p < 10-10
36.2
[28.3-44.1]
p = 10-8
28.8
[19.9-37.6]
p = 10-8
29.1
[20.9-37.4]
p = 10-8
  1. 2-tailed unpaired Student's t-tests with Bonferroni corrections following ANOVA (p < 0.05): * vs. HC of Cohort 1 and ** vs. HC of Cohort 2.