| Cohort 1 | Cohort 2 | |||||
---|---|---|---|---|---|---|---|
Domains | HC n = 300 | CFS * n = 170 | HC n = 19 | CFS ** N = 49 | CFS+MO** n = 28 | CFS+MA** N = 12 | CFS+T ** n = 9 |
General Fatigue | 10.4 [9.9-10.9] | 16.4 [15.9-16.9] p < 10-10 | 8.2 [6.7-9.6] | 17.9 [17.2-18.6] p < 10-10 | 18.3 [17.5-19.1] p < 10-10 | 18.5 [17.0-20.0] p = 10-10 | 15.9 [13.9-17.8] p = 10-6 |
Physical Fatigue | 9.4 [8.9-9.9] | 14.6 [14.0-15.2] p < 10-10 | 8.1 [5.8-10.3] | 16.0 [15.1-16.9] p < 10-10 | 16.3 [15.1-17.5] p = 10-8 | 16.3 [14.6-17.9] p = 0.00002 | 14.8 [12.2-16.5] p = 0.002 |
Reduced Activity | 8.4 [8.0-8.8] | 12.7 [12.1-13.4] p < 10-10 | 7.4 [5.7-9.2] | 16.2 [15.2-17.1] p < 10-10 | 16.3 [15.0-17.5] p < 10-10 | 17.4 [15.8-19.1] p = 10-8 | 14.3 [12.2-16.5] p = 0.00001 |
Reduced Motivation | 8.2 [7.6-8.7] | 11.1 [10.5-11.7] p < 10-10 | 8.2 [6.7-9.7] | 11.9 [10.7-13.1] P = 0.001 | 11.8 [10.1-13.4] p = 0.005 | 13.0 [10.3-15.7] p = 0.003 | 10.7 [8.8-12.5] |
Mental Fatigue | 8.8 [8.3-9.3] | 13.2 [12.5-13.9] p < 10-10 | 8.5 [6.9-10.1] | 15.0 [13.8-16.1] P = 10-8 | 14.7 [13.2-16.1] p = 10-6 | 16.8 [14.7-18.8] p = 10-6 | 13.3 [10.4-16.2] p = 0.004 |