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Table 4 Evolution of the HFMS scores in the two age groups of SMA patients during the VPA treatment.

From: Evaluation of muscle strength and motor abilities in children with type II and III spinal muscle atrophy treated with valproic acid

 

Evaluations

 

Age

1

2

3

4

5

p (*)

≤ 6 years

21.5 ± 8.8

22.5 ± 9.5

22.9 ± 8.7

23.2 ± 8.3

23.5 ± 8.7

0.240

> 6 years

12.2 ± 8.8

12.7 ± 9.0

12.8 ± 9.0

13.0 ± 9.2

12.8 ± 9.1

0.922

p (**)

0.018

0.012

0.010

0.009

0.007

 
  1. * Comparison between the first evaluation with the subsequent ones
  2. ** Comparison between both groups of patients in each evaluation