Figure 2From: Molecular and biochemical characterisation of a novel mutation in POLGassociated with Alpers syndrome Quantification of mtDNA. Quantification of mtDNA depletion in muscle, liver and fibroblasts of the patient. mtDNA content was measured by qPCR and normalised to a nuclear gene (B2M). Control mean and +/-1SD: fibroblast 832 +/-280; skeletal muscle 2878 +/-766 and liver 1515 +/-192.Back to article page