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Table 1 Comparison of the demographic characteristics and dementia-related scale scores of the participants

From: Identification of peripheral inflammatory markers between normal control and Alzheimer's disease

 

NC (n = 21)

MCI (n = 20)

AD (n = 18)

p-value

*Tukey HSD

Age

75.5 ± 1.3

76.1 ± 2.8

75.9 ± 6.0

0.884

 

Gender

   

0.954

 

   Male (%)

10 (47.6)

9 (45.0)

9 (50.0)

  

   Female (%)

11 (52.4)

11 (55.0)

9 (50.0)

  

Educational level (y)

11.6 ± 3.8

6.6 ± 4.9

4.7 ± 4.1

<0.0001

a > b = c

BMI (%)

24.7 ±.2.0

24.9 ± 3.0

22.7 ± 2.3

0.016

a = b > c

CVD (%)

38.1

70.0

33.3

0.044

 

NSAIDs use (%)

19.1

5.0

11.1

0.423

 

MMSE

27.9 ± 1.6

24.3 ± 2.6

15.9 ± 6.1

<0.0001

a > b > c

CDR score

0

0.1 ± 0.2

1.1 ± 0.8

<0.0001

a < b = c

GDS score

6.4 ± 3.5

7.2 ± 4.3

8.1 ± 6.7

0.547

a = b = c

WBC (1000/ul)

5.7 ± 1.3

6.4 ± 1.3

6.9 ± 1.4

0.046

a = b < c

Fibrinogen (mg/dL)

318.8 ± 52.4

351.8 ± 67.8

356.3 ± 107.7

0.252

a = b = c

Homocystein (umol)

15.9 ± 5.5

17.7 ± 4.8

19.4 ± 10.7

0.339

a = b = c

  1. Data are expressed as means ± standard deviation unless otherwise indicated.
  2. Independent χ2 test and one-way analysis of variance (ANOVA) were used to compare differences between diagnosis states. *Tukey's Studentized Range (HSD) Test
  3. NC: Normal control.
  4. MCI: Mild cognitive impairment.
  5. AD: Alzheimer disease.
  6. BMI: Body mass index
  7. CVD: Cardiovascular diseases
  8. NSAIDs: Non-steroidal anti-inflammatory drugs
  9. MMSE: Mini Mental State Examination
  10. CDR: Clinical Dementia Rating
  11. WBC: White Blood Cell