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Table 5 Cognition at baseline versus normative data

From: Cognitive performance in relapsing remitting multiple sclerosis: A longitudinal study in daily practice using a brief computerized cognitive battery

 

Mean (SD)

 

d

p

Measure

Normative Data (N≥1688)

RRMS (N = 43)

  

Power of Attention

1083 (107)

1228 (162)

1.4

<0.0001

Continuity of Attention

64 (11.3)

57.3 (11.9)

0.6

0.0006

Quality of Working Memory

1.78 (0.21)

1.82 (0.16)

-0.2

0.1183

Quality of Episodic Memory

186 (53)

180 (56)

0.1

0.5296

Speed of Memory

3106 (698)

3589 (850)

0.7

0.0006

DSST^

58.7 (17.8)

41.5 (9.6)

1.1

<0.0001

  1. SD, Standard Deviation; d, Cohen's d (effect size); RRMS, Relapsing Remitting Multiple Sclerosis; DSST, Digit Symbol Substitution Test. ^DSST Normative Data N = 151; < 0.3 small effect size; 0.3 to 0.7 moderate effect size; > 0.7 large effect size. Correcting for multiplicity p-values are statistically significant at p < 0.008.