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Table 7 Change over time for CDR domain scores, CDR composite, DSST, MSFC components and MSFC

From: Cognitive performance in relapsing remitting multiple sclerosis: A longitudinal study in daily practice using a brief computerized cognitive battery

  Main Effect of Time-point
Power of Attention F 0.39 [8,300] p = 0.928
Continuity of Attention F 0.68 [8,300] p = 0.708
Quality of Working Memory F 5.6 [8,300] p < 0.0001
Quality of Episodic Memory F 0.64 [8,300] p = 0.7458
Speed of Memory F 0.67 [8,300] p = 0.7157
CDR composite F 1.42 [8,274] p = 0.1876
DSST F 1.48 [8,300] p = 0.1627
Timed 25-FWT F 1.15 [7,267] p = 0.33
9-HPT F 0.51 [7,265] p = 0.8238
PASAT 3" F 6.96 [7,266] p < 0.0001
MSFC F 1.68 [7,264] p = 0.1152
  1. F, F ratio (PROC Mixed analysis of covariance output); CDR, Cognitive Drug Research, DSST, Digit Symbol Substitution Test; MSFC, Multiple Sclerosis Functional Composite; Timed 25-FWT, Timed 25 Foot Walk Test; 9-HPT, 9 Hole Peg Test, PASAT 3", Paced Auditory Serial Addition Test 3 sec. Correcting for multiplicity p-values are statistically significant at p < 0.005.