Table 2 Demographic and Clinical Characteristics
Characteristic | Non-PGB (N = 157)† | PGB monotherapy (N = 577)† | PGB add-on (N = 575)† | P ‡ |
|---|---|---|---|---|
Gender (female), n (%) | 87 (55.3) | 349 (60.4) | 332 (57.8) | 0.4874 |
Age, mean (SD) | 60.4 (12.4) | 58.6 (12.5) | 59.7 (13.0) | 0.1486 |
Body Mass Index (Kg/m2) | 26.9 (3,5) | 27.3 (3,8) | 27.3 (3,9) | 0.4673 |
Civil status (married or with couple), n (%) | 108 (69.0%) | 383 (66.4%) | 389 (67.6%) | 0.6041 |
Working status, n (%) | ||||
Active | 51 (32.5) | 200 (34.6) | 178 (31.0) | 0.3835 |
Housewife | 29 (18.7) | 73 (12.7) | 86 (14.9) | |
Off sick | 9 (6.0) | 44 (7.6) | 61 (10.6) | |
Unemployed | 3 (1.8) | 15 (2.6) | 11 (1.9) | |
Retired | 56 (35.5) | 204 (35.3) | 213 (37.0) | |
Unknown | 8 (5.4) | 41 (7.1) | 26 (4.6) | |
Elapsed time from diagnosis (years), mean (SD) | 2.1 (3.1) | 1.9 (3.4) | 2.0 (3.4) | 0.7130 |
Diagnosis (%) | ||||
Diabetic neuropathy | 47.9 | 58.2 | 53.0 | 0.2852 |
Post-herpetic neuralgia | 37.2 | 31.2 | 36.9 | |
Trigeminal neuralgia | 14.9 | 10.7 | 10.1 | |
DN4 Questionnaire, mean (SD) | 6.4 (1.7) | 6.8 (1.8) | 6.8 (1.7) | 0.033 |
SF-MPQ, mean (SD) | ||||
Total | 18.5 (8.0) | 21.0 (8.4) | 21.1 (8.4) | 0.002 |
PPI (0 - 5) | 2.4 (0.9) | 2.7 (0.8) | 2.7 (0.9) | <0.001 |
VAS (0 - 100) | 66.8 (17.6) | 71.4 (15.2) | 72.6 (15.7) | <0.001 |
Previous treatments#, n (%) | ||||
Mean (SD) | 2.4 (1.3) | 2.0 (1.1) | 2.6 (1.4) | <0.001 |
NSAID$ | 66 (42.0) | 140 (24.3) | 311 (54.1) | <0.001 |
Paracetamol | 69 (43.7) | 224 (38.8) | 266 (46.3) | 0.030 |
Metamizol | 40 (25.7) | 119 (20.7) | 168 (29.2) | 0.003 |
Opiates | 70 (44.3) | 153 (26.6) | 244 (42.4) | <0.001 |
AED | 43 (27.5) | 128 (22.2) | 108 (18.8) | 0.043 |
Tricyclic drugs | 17 (10.8) | 59 (10.2) | 67 (11.7) | 0.704 |
Others§ | 12 (7.8) | 35 (6.0) | 79 (13.8) | <0.001 |