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Table 3 Use of drugs, non-pharmacological treatments, and complementary tests during the study by treatment group

From: A Cost-Consequences analysis of the effect of Pregabalin in the treatment of peripheral Neuropathic Pain in routine medical practice in Primary Care settings

Resource

Non-PGB

(N = 157)§

PGB monotherapy

(N = 577)§

PGB add-on

(N = 575)§

p between groups

 

Baseline

Final

Baseline

Final

Baseline

Final

Baseline

Final$

Drug treatment

Mean number (SD)

2.4 (1.3)

2.2 (1.2)

2.0 (1.1)

1.0 (0.0)*

2.6 (1.4)

2.7 (1.0)

<0.001

<0.001

Non-pharmacological treatments; N (%)

   Physiotherapy

45 (30.8)

23 (15.8)*

168 (34.1)

73 (14.8)*

194 (38.2)

116 (22.8)*

0.180

0.011

   TENS

16 (11.4)

12 (8.6)

45 (9.6)

24 (5.1)*

52 (10.7)

32 (6.6)┼

0.766

0.375

   Infiltrations

21 (14.9)

11 (7.8)╪

51 (10.8)

20 (4.2)*

72 (14.8)

21 (4.3)*

0.154

0.195

   Electrotherapy

18 (12.9)

10 (7.1)╪

30 (6.5)

12 (2.6)*

48 (10.0)

17 (3.6)*

0.033

0.190

   Blockade

3 (2.2)

1 (0.7)

8 (1.7)

4 (0.9)╪

5 (1.1)

2 (0.4)

0.552

0.858

   Iontophoresis

4 (2.9)

0 (0.0)╪

1 (0.2)

0 (0.0)

7 (1.5)

1 (0.2)╪

0.019

0.530

   Spinal stimulator

1 (0.7)

0 (0.0)

2 (0.4)

1 (0.2)

4 (0.8)

2 (0.4)

0.727

0.700

   Pumps

1 (0.8)

0 (0.0)

0 (0.0)

0 (0.0)

3 (0.6)

0 (0.0)

0.214

1.000

   Hydrotherapy

3 (1.8)

0 (0.0)

10 (1.7)

9 (1.5)

15 (2.5)

7 (1.2)

0.552

0.199

   Short wave

3 (1.8)

1 (0.6)

7 (1.2)

1 (0.2)╪

22 (3.7)

12 (2.0)╪

0.013

0.053

   Magnetotherapy

1 (0.6)

3 (1.8)

3 (0.5)

2 (0.3)

6 (1.0)

2 (0.3)

0.568

0.034

   Acupuncture

1 (0.6)

0 (0.0)

4 (0.7)

0 (0.0)

3 (0.5)

0 (0.0)

0.938

1.000

Complementary tests; N (%)

   CT

25 (15.0)

17 (10.2)

155 (25.9)

39 (6.5)*

193 (32.8)

69 (11.7)*

<0.001

0.013

   Resonance

60 (35.9)

32 (19.2)*

193 (32.3)

62 (10.4)*

224 (38.0)

88 (14.9)*

0.114

0.012

   Electromyogram

40 (24.0)

22 (13.2)╪

164 (27.4)

51 (8.5)*

215 (36.5)

68 (11.5)*

0.001

0.109

   ECHO Doppler

12 (7.2)

8 (4.8)

50 (8.4)

14 (2.3)*

59 (10.0)

20 (3.4)

0.424

0.194

   Thermogram

6 (3.6)

1 (0.6)

4 (0.7)

3 (0.5)

13 (2.2)

10 (1.7)

0.016

0.151

   X-rays

111 (66.5)

51 (30.5)*

363 (60.7)

123 (20.6)*

410 (69.6)

145 (24.6)*

0.005

0.058

   General analysis

124 (74.3)

73 (43.7)*

427 (71.4)

198 (33.1)*

450 (76.4)

233 (39.6)*

0.146

0.032

   Gammagram

12 (7.2)

5 (3.0)

41 (6.9)

11 (1.8)*

51 (8.7)

24 (4.1)*

0.491

0.129

  1. SD: standard deviation; TENS: Transcutaneous electric neurostimulation; CT: Computerized tomography; * p < 0.0001; ┼ p < 0.001; ╪ p<0.05 vs. intragroup baseline value. §Total number of analyzed patients; some patients did not report all data. $Between groups changes comparison adjusted by baseline values and number of previous drugs.
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BMC Neurology

ISSN: 1471-2377

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