Skip to main content

Table 4 Baseline values and change on use of medical visits, hospitalizations, and decreased work productivity after 12 weeks by group.

From: A Cost-Consequences analysis of the effect of Pregabalin in the treatment of peripheral Neuropathic Pain in routine medical practice in Primary Care settings

Resource Non-PGB
(N = 157)§
PGB monotherapy
(N = 577)§
PGB add-on
(N = 575)§
p between groups
Number of medical visits Baseline Change Baseline Change Baseline Change Baseline Change$
   Total 8.8 (7.0) -2.4 (6.3) 9.6 (8.1) -4.3 (6.4) 10.3 (7.1) -4.3 (6.3) 0.050 0.001
   Primary care 5.9 (4.1) -1.2 (4.5) 6.7 (4.9) -2.3 (4.6) 7.1 (4.8) -2.2 (4.3) 0.011 0.064
   Pain unit 0.5 (0.9) 0.0 (0.8) 0.7 (1.6) -0.5 (1.4) 0.6 (1.2) -0.3 (1.1) 0.164 0.003
   Specialist 1.4 (1.7) -0.5 (1.5) 1.2 (1.5) -0.8 (1.4) 1.5 (1.7) -0.8 (1.7) 0.033 0.007
   Emergency room 1.6 (2.8) -0.7 (1.9) 1.5 (3.1) -1.0 (2.3) 1.6 (2.4) -1.0 (2.1) 0.847 0.012
Hospitalized (N, %) 11 (7.7) 4 (2.8) 9 (1.8) 1 (0.2) 34 (6.4) 14 (2.6) 0.001 0.074
Productivity Baseline Change Baseline Change Baseline Change Baseline Change
   Days of absenteeism due to pain 15.7 (21.7) -5.4 (18.7) 19.1 (23.4) -10.4 (18.8)* 24.4 (26.9) -12.9 (20.4)* 0.001 0.059
   Days working with pain 35.0 (29.0) -11.8 (26.6)* 40.3 (30.2) -23.7 (28.6)* 43.2 (29.9) -22.6 (28.6)* 0.012 0.001
   Labour productivity£ 48.1 (21.3) +16.8 (79.7) 46.9 (21.1) +21.6 (24.0)* 43.4 (21.6) +18.7 (23.2)* 0.007 0.064
   LWDE 31.4 (25.9) -14.0 (22.8)* 35.9 (26.7) -22.1 (23.2)* 41.6 (28.3) -23.1 (24.3)* <0.001 0.005
  1. Values expressed as means (standard deviation); LWDE: Lost -workdays equivalents; * p < 0.0001; p < 0.001; p<0.05 vs. intragroup baseline values. §Total number of analyzed patients; some patients did not report all data; $Between groups changes comparison adjusted by baseline values and number of previous drugs. £In days working with pain.
\