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Table 3 Risk factors of Ischemic stroke and their Population Attributable Fraction based on Cox proportional hazard model*

From: Risk factors for ischemic stroke; results from 9 years of follow-up in a population based cohort of Iran

 

HR

95% CI

P-value

PAF (%)

Model including binary variables

Age, ≥ 65 years

2.04

(1.21- 3.44)

0.007

24

Sex, male

1.93

(1.90- 3.43)

0.024

28.4

Smoking

1.73

(0.97- 3.08)

0.063

14.5

Hypertension

2.73

(1.55- 4.81)

0.001

44.7

Diabetes

2.38

(1.42- 3.99)

0.001

24.7

Chronic Kidney Disease

2.09

(1.22- 3.58)

0.007

30.8

Model including continuous variables

Age, years

1.07

(1.03-1.11)

<0.001

 

Sex, male

1.69

(0.95-3.00)

0.072

 

Smoking

1.83

(1.04-3.25)

0.038

 

Systolic blood pressure, cmHg

1.13

(0.99-1.28)

0.075

 

Diastolic blood pressure, cmHg

1.51

(1.16-1.96)

0.002

 

Fasting plasma glucose, mmol/l

1.11

(1.03-1.20)

0.009

 

GFR, mL/min/1.73 m2

0.97

(0.94-0.99)

0.014

 
  1. * These risk factors remained in the model through a forward stepwise method; other variables (obesity, high waist circumference, low HDL cholesterol, hypertriglyceridemia, hypercholesterolemia, intervention and family history of premature cardiovascular disease)were excluded from the model because of p < 0.2 for entry or p > 0.1 for removal. Hosmer-Lemeshow chi-square (modified version for survival data) was <20 indicating a good fitness of the model.
  2. HR: Hazard Ratio; CI: Confidence Interval; PAF: Population Attributable Fraction; GFR: Glomerular Filtration Rate.
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BMC Neurology

ISSN: 1471-2377

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