| |
Mean difference (95% CI) between before and after 6 months
|
Mean difference (95% CI) between before and after 12 months
|
Time
|
Group
|
Group × time
|
|---|
| |
Exercise (n=25)
|
Control (n=25)
|
Exercise (n=25)
|
Control (n=25)
|
df
|
F value
|
P value
|
df
|
F value
|
P value
|
df
|
F value
|
P value
|
|---|
|
MMSE
|
0.32 (−0.96−1.60)
|
−1.37 (−2.66−−0.07)
|
−0.47 (−1.75−0.81)
|
−0.44 (−1.74−0.86)
|
92.1
|
1.17
|
0.32 d
|
48.0
|
2.2
|
0.14 g
|
92.1
|
3.4
|
0.04
|
|
WMS-LM I
|
3.83 (1.40−6.25)
|
0.60 (−1.87−3.06)
|
4.62 (2.19−7.05)
|
5.00 (2.53−7.46)
|
90.9
|
23.0
|
<0.01 a, b, e, f
|
47.8
|
0.9
|
0.34 g
|
90.9
|
3.9
|
0.03
|
|
WMS-LM II
|
3.79 (1.49−6.10)
|
2.09 (−0.25−4.43)
|
5.13 (2.82−7.43)
|
6.20 (3.86−8.54)
|
91.1
|
35.4
|
<0.01 a, b, e, f
|
48.1
|
1.1
|
0.30
|
91.1
|
2.1
|
0.13
|
|
DSC
|
−0.19 (−4.20−3.81)
|
3.27 (−0.80−7.34)
|
3.64 (−0.36−7.64)
|
3.73 (−0.34−7.80)
|
90.4
|
5.0
|
<0.01
|
48.0
|
0.2
|
0.65
|
90.4
|
1.4
|
0.25
|
|
LVFT
|
2.87 (0.57−5.17)
|
−0.97 (−3.31−1.37)
|
2.99 (0.69−5.30)
|
1.61 (−0.73−3.95)
|
91.2
|
5.9
|
<0.01
|
48.3
|
0.3
|
0.59
|
91.2
|
4.1
|
0.02
|
|
CVFT
|
1.54 (−1.27−4.35)
|
−1.81 (−4.67−1.04)
|
1.33 (−1.48−4.14)
|
−1.61 (−4.46−1.25)
|
91.2
|
0.02
|
0.98
|
48.5
|
3.1
|
0.08
|
91.2
|
2.5
|
0.09
|
|
SCWT-I
|
−3.30 (−7.56−0.96)
|
−0.98 (−5.30−3.34)
|
−3.68 (−7.94−0.58)
|
−3.20 (−7.52−1.12)
|
91.5
|
3.9
|
0.02
|
47.7
|
0.73
|
0.40
|
91.5
|
0.5
|
0.62
|
|
SCWT-III
|
−4.70 (−12.72−3.33)
|
0.15 (−8.00−8.30)
|
−2.61 (−10.64−5.42)
|
−4.57 (−12.72−3.58)
|
92.0
|
1.2
|
0.31
|
48.8
|
0.009
|
0.92
|
92.0
|
1.1
|
0.34
|
- MMSE; mini-mental state examination, WMS-LM; Logical Memory subtest of the Wechsler memory scale-revised, DSC; digit-symbol cording, LVFT; letter verbal fluency test, CVFT; category verbal fluency test, SCWT; Stroop Color and Word Test, TMIG; Tokyo Metropolitan Institute of Gerontology index.
-
a P < .05; significant differences between before and after 6 months in the exercise group, b P < .05; significant differences between before and after 12 months in the exercise group, c P < .05; significant differences between after 6 months and 12 months in the exercise group, d P < .05; significant differences between before and after 6 months in the control group, e P < .05; significant differences between before and after 12 months in the control group, f P < .05; significant differences between after 6 months and 12 months in the control group, g P < .05; significant differences between the exercise and control groups at after 6 months, h P < .01; significant differences between the exercise and control groups at after 12 months.
