Deterioration of Parkinson's disease during hospitalization: survey of 684 patients

Gerlach, Oliver HH; Broen, Martijn PG; van Domburg, Peter HMF; Vermeij, Ad J; Weber, Wim EJ

doi:10.1186/1471-2377-12-13

BMC Neurology

Table 1 Patient and hospitalization characteristics

From: Deterioration of Parkinson's disease during hospitalization: survey of 684 patients

		MUMC		OMC		CHE		Total		Homogeneity^$
Total questionnaires (N)		447		230		207		884
Response rate (%)		72		84		81		77
Admitted patients (N)		53		34		36		123
Total hospitalizations (N)		61		47		51		159
Age (yr)		71 [SD = 10.4]		75 [SD = 7.6]		71 [SD = 8.5]		72 [SD = 9.2]		0.87
Disease duration (yr)		9.6 [SD = 7.0]		9.1 [SD = 7.2]		10.7 [SD = 6.9]		9.8 [SD = 7.0]		0.49
LED-value (mg/day)		554		761		855		711		0.004
		N*	%*	N*	%*	N*	%*	N*	%*
Gender
	Women	28	46	15	32	14	28	57	36	0.04
	Men	33	54	32	68	37	72	102	64
Hoehn&Yahr
	stage < III	24	39	20	43	13	25	57	36	0.12
	stage III, IV	33	54	25	53	33	65	91	57	0.32
	stage V	3	5	2	4	5	10	10	6	0.33
	Don't know/missing	1	2	0	0	0	0	1	1
On-off fluctuations
	Yes	27	44	14	30	21	41	62	39	0.61
	No	33	54	33	70	30	59	96	60
	Don't know/missing	1	2	0	0	0	0	1	1
Cognitive problems
	Yes	20	33	24	51	29	57	72	46	0.009
	No	41	67	23	49	22	43	86	54
	Don't know/missing	0	0	0	0	0	0	0	0
Deterioration during admission
	Yes	13	21	10	21	11	22	34	21	0.84
	No	45	74	30	64	35	69	110	69
	Don't know/missing	3	5	7	15	5	10	15	9
Complications during admission
	None	40	66	30	64	35	69	105	66	0.76
	One or more complications	21	34	15	32	16	31	52	33	0.30
	Confusion	13	21	11	23	11	22	35	22	0.91
	Urinary tract infection	4	7	6	13	2	4	12	8	0.70
	Emotional disturbance	6	10	0	0	0	0	6	4	0.004
	Pneumonia	0	0	2	4	2	4	4	3	0.17
	Memory complaints	2	3	0	0	3	6	5	3	0.50
	Falls	0	0	2	4	0	0	2	1	0.87
	Other	2	3	0	0	3	6	5	3	0.50
	Don't know/missing	0	0	2	4	0	0	2	1
Medication distribution
	Good	40	66	29	62	39	76	108	68	0.15
	Bad	18	30	16	34	8	16	42	26
	Don't know/missing	3	5	2	4	4	8	9	6
Surgery
	Yes	39	64	21	45	31	61	91	57	0.63
	No	22	36	26	55	20	39	68	43
	Don't know/missing	0	0	0	0	0	0	0	0
Ward
	Neurologic	11	18	6	13	11	22	28	18	0.68
	Non-neurologic	48	79	41	87	39	76	128	81
	Don't know/missing	2	3	0	0	1	2	3	2
Involvement of paramedics
	Yes	23	38	29	62	8	16	60	38	0.025
	No	34	56	14	30	41	80	89	56
	Don't know/missing	4	7	4	9	2	4	10	6
Consultation of PD nurse specialist ^#
	Yes	14	23	20	43	5	10	39	25	0.14
	No	45	74	24	51	44	86	113	71
	Don't know/missing	2	3	3	6	2	4	7	4

* N; number and percentage of total admissions
^# Non-neurological ward
$ For homogeneity between different centres the Pearson Correlation and Spearman's rho tests were used. P-values are shown. P-value < 0.05 is considered significant.
Abbreviations: MUMC, Maastricht University Medical Centre; OMC, Orbis Medical Centre; CHE, Catharina Hospital Eindhoven; N, number; SD, standard deviation; LED-value, Levodopa Equivalent Dose; PD, Parkinson's disease

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ISSN: 1471-2377

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