Deterioration of Parkinson's disease during hospitalization: survey of 684 patients

BMC Neurology

Table 2 Effect of patient, Parkinson's disease characteristics, and factors during hospitalization on deterioration of Parkinson's disease

	Deterioration (N = 34)
Possible risk factors	N	P-value*	OR [95%-CI]
Gender
Male	25	0.39
Age
≥ 70 years	20	0.42
≥ 80 years	5	0.47
≥ 85 years	5	0.13
Disease duration
≥ 8 years	17	0.82
≥ 10 years	9	0.18
≥ 12 years	8	0.36
Hoehn&Yahr
stage ≥ II	27	0.50
stage ≥ III	27	0.07
On-off fluctuations	16	0.38
Cognitive problems	19	0.18
LED-value
> 500 mg/day	15	0.60
> 600 mg/day	15	0.07
> 700 mg/day	15	0.003	4.4 [1.7-11.5]
Complications ≥ 1	16	0.04	2.5 [1.1-5.6]
Confusion	10	0.23
Infections	7	0.00	6.7 [1.8-24.7]
wrong medication distribution	18	0.00	5.8 [2.5-13.7]
surgery	17	0.26
Non-neurologic ward	27	0.60
No involvement of paramedics	16	0.15
No-consultation of PD nurse specialist#	17	0.04	0.3 [0.1-0.7]

*P-value < 0.05 is considered significant
^# Non-neurological ward
Abbreviations: N, number; OR, Odds-ratio; 95%-CI, 95%-confidence interval; LED, Levodopa equivalent dose; PD, Parkinson's Disease

ISSN: 1471-2377