Brain CT and MRI on admission and after treatment in a 26 year-old SLE patient who presented with seizure. CT (A) shows normal but T2-weighted image (B) shows high signal lesions in subcortical left centroparietal white matter. On contrast-enhanced T1-weighted sequence (C), there is minimal enhancement at the periphery. Diffusion-weighted image (D) shows high-signal intensity area in corresponding lesion areas. Corresponding ADC map (E) reveals high signal intensity area. The abnormal lesion completely diminished in T2-weighted image (F) after 8 months of steroid therapy. DWI (G) shows high signal lesions and ADC (H) reveals lesion low intensity.