Table 1 Baseline Characteristics
Characteristics | FVIIa Group (n = 45) | Comparison Group (n = 34) | p-value |
|---|---|---|---|
Age | 73 [69–76] | 77 [74–81] | 0.07 |
Female gender | 22 (49%) | 19 (56%) | 0.53 |
Diagnosis | 0.77 | ||
Intra-parenchymal hemorrhage | 22 (49%) | 14 (41%) | |
Subdural hemorrhage | 19 (42%) | 17 (50%) | |
Subarachnoid hemorrhage | 4 (9%) | 3 (9%) | |
Indication for anticoagulation | 0.79 | ||
AF | 29 (64%) | 21 (62%) | |
Mechanical valve | 3 (7%) | 2 (6%) | |
DVT/PE | 7 (16%) | 5 (15%) | |
Stroke | 2 (4%) | 2 (6%) | |
Cardiomyopathy | 1 (2%) | 3 (9%) | |
Unknown | 3 (7%) | 1 (3%) | |
Prior Thromboembolism History | |||
History of AF | 33 (73%) | 23 (68%) | 0.58 |
History of CAD | 17 (38%) | 11 (32%) | 0.62 |
History of DVT/PE | 10 (22%) | 6 (18%) | 0.61 |
History of stroke/TIA | 8 (18%) | 10 (29%) | 0.22 |
History of cancer | 5 (11%) | 11 (32%) | 0.02 |
Abnormal baseline EKG | 35 (78%) | 29 (85%) | 0.01 |
T wave abnormality | 11 (24%) | 2 (6%) | |
ST abnormality | 11 (22%) | 12 (35%) | |
Conduction block | 5 (11%) | 7 (21%) | |
Arrhythmia | 6 (13%) | 6 (18%) | |
QTc prolongation | 1 (2%) | 2 (6%) | |
Left ventricular hypertrophy | 2 (4%) | 0 | |
Initial INR | 2.47 [2.17 – 2.78] | 2.22 [1.98 – 2.47] | 0.36 |
Initial PTT | 40.3 [35.8 – 44.8] | 36.8 [34.2 – 39.4] | 0.75 |