Signal alterations of the basal ganglia in the differential diagnosis of Parkinson’s disease: a retrospective case-controlled MRI data bank analysis

Table 2 Statistical calculation of sensitivity, specificity, positive predictive value, and negative predictive value (including leave one out method)

	Sensitivity	Specificity	PPV	NPV
ASN > TH_SN	0.72 ± 0.08	0.82 ± 0.02	0.72 ± 0.04	0.82 ± 0.06
AGPI > TH_GPI	0.84 ± 0.06	0.80 ± 0.03	0.73 ± 0.04	0.89 ± 0.04
Combination	0.86 ± 0.04	0.77 ± 0.05	0.70 ± 0.06	0.90 ± 0.04

Table 2 Statistical measures for defined thresholds: average substantia nigra (ASN) value above threshold (THSN), average globus pallidus internus (AGPI) above threshold (THGPI), and the combination, i.e. ASN > THSN or AGPI > THGPI. Predicted residual error sum of squares (PRESS) values were calculated by the leave one out method. Results are presented as statistical measure ± PRESS. PPV positive predictive value, NPV negative predictive value.

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