Aspirin for the prevention of cognitive decline in the elderly: rationale and design of a neuro-vascular imaging study (ENVIS-ion)

Table 1 Measurement schedule for the participants of the ENVIS-ion trial.

	Recruitment, Screening & Baseline	Annualreview (1 yr)	Annualreview (3 yr)	Annualreview (5 yr)
ENVIS-ion study
Brain MRI & RVI	X		X
Additional cognitive function tests^a	X		X
ASPREE parent study
Inclusion/exclusion criteria; informed consent	X
Cognitive function tests^b	X	X	X	X
Demographics & physical measures^c	X	X	X	X
Blood pressure & cardiovascular biomarkers^d	X	X	X	X
Health behaviors & lifestyle measurements^e	X	X	X	X

^a Stoop test (Victoria version) & Color Trails test ^b 3 MS, Digit Symbol Modalities test, COWAT, and Hopkins Verbal hearing test ^c Includes first language, level of education, height, weight, abdominal circumference, family history & co-morbidity; ^d Includes total cholesterol, LDL-Cholesterol, HDL-Cholesterol, triglycerides, C-Reactive Protein, Hemoglobin, fasting glucose & creatinine;^e Includes physical activity, smoking history & alcohol use, SF-36 & IADL

ISSN: 1471-2377