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Figure 2 | BMC Neurology

Figure 2

From: Primary epidural lymphocyte-depleted Hodgkin’s lymphoma of the thoracic spine – presentation of a rare disease variant

Figure 2

Fresh frozen and permanent histological analysis of the tumor. A) Initial fresh frozen sample obtained intraoperatively suggestive of a poorly differentiated carcinoma. B) H&E permanent section showing scattered small lymphocytes admixed amongst numerous large neoplastic Reed Sternberg cells. C) Neoplastic RS cells stained positive for CD30, a marker of lymphocyte activation. Paucity of lymphocytes admixed with a background of fibrosis suggests that this is lymphocyte-depleted subtype of HL.

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