Skip to main content

Table 1 Baseline clinical characteristics, vascular risk factors, stroke subtype, biochemical parameters and neuroimaging findings in patients with and without recurrence

From: Oxidative stress markers are associated to vascular recurrence in non-cardioembolic stroke patients non-treated with statins

 

Primary end-point

 

No n = 409

Yes n = 68

p

Age, years

70.9 ± 7.2

71.4 ± 8.2

0.687

Male, %

68.7

73.5

0.479

Weight, kg

75.1 ± 11.8

78.5 ± 14.5

0.106

Waist circumference, cm

101.3 ± 12.6

103.7 ± 14.4

0.203

Systolic blood pressure, mm Hg

152.8 ± 25.2

161.1 ± 26.4

0.017

Diastolic blood pressure, mm Hg

82.9 ± 13.0

85.2 ± 14.3

0.141

Arterial hypertension, %

72.5

69.1

0.562

Diabetes mellitus, %

34.4

45.6

0.078

Active smoker, %

29.6

26.5

0.667

Alcohol intake, %

4.9

8.8

0.242

Dyslipemia, %

44.2

48.5

0.513

Ischaemic CHD, %

11.5

16.2

0.316

Symptomatic PAD, %

6.0

23.5

<0.0001

Treatment before index stroke

  Antiplatelets, %

25.2

28.4

0.651

  Statins, %

28.6

31.3

0.664

  Antihypertensive, %

62.2

60.3

0.788

  Hypoglycemics, %

26.9

36.4

0.139

Treatment at discharge

  Antiplatelets, %

99.3

100

0.628

  Statins, %

73.8

73.5

0.533

  Antihypertensive, %

76.8

76.1

0.505

  Hypoglycemics, %

33.0

35.3

0.404

Stroke subtype

  

<0.0001

  Atherothrombotic probable, %

14.8

35.3

 

  Atherothrombotic posible, %

43.7

41.2

 

  Lacunar, %

21.0

13.2

 

  Cryptogenic, %

20.5

10.3

 

Modified Rankin at discharge

1 [0, 2]

2 [1, 2]

0.034

ABI

1.00 ± 0.23

0.92 ± 0.29

<0.0001

IMT, mm

0.91 ± 0.34

0.96 ± 0.44

0.043

ICA stenosis > 50 % homolateral, %

14.8

35.8

<0.0001

ICA stenosis > 50 % contralateral, %

5.7

16.4

0.004

Echogenicity of plaques

  

0.493

  Type I, %

15.0

10.7

 

  Type II, %

14.7

17.9

 

  Type III, %

24.5

21.4

 

  Type IV, %

37.9

46.4

 

  Type V, %

8.2

3.6

 

Plaques surface

  

0.001

  Smooth and even, %

75.0

50.0

 

  Uneven, %

23.7

48.3

 

  Ulcerated, %

1.3

1.7

 

8-OHDG (ng/mL)

33.11 ± 15.18

40.06 ± 24.70

0.003

Cu/Zn SOD (ng/mL)

44.37[31.06-70.06]

52.75 [36.73-89.59]

0.062

ox-LDL (ng/mL)

54.83 [45.71-69.36]

53.43[43.34-62.52]

0.241