Primary end-point | |||
---|---|---|---|
No n = 409 | Yes n = 68 | p | |
Age, years | 70.9 ± 7.2 | 71.4 ± 8.2 | 0.687 |
Male, % | 68.7 | 73.5 | 0.479 |
Weight, kg | 75.1 ± 11.8 | 78.5 ± 14.5 | 0.106 |
Waist circumference, cm | 101.3 ± 12.6 | 103.7 ± 14.4 | 0.203 |
Systolic blood pressure, mm Hg | 152.8 ± 25.2 | 161.1 ± 26.4 | 0.017 |
Diastolic blood pressure, mm Hg | 82.9 ± 13.0 | 85.2 ± 14.3 | 0.141 |
Arterial hypertension, % | 72.5 | 69.1 | 0.562 |
Diabetes mellitus, % | 34.4 | 45.6 | 0.078 |
Active smoker, % | 29.6 | 26.5 | 0.667 |
Alcohol intake, % | 4.9 | 8.8 | 0.242 |
Dyslipemia, % | 44.2 | 48.5 | 0.513 |
Ischaemic CHD, % | 11.5 | 16.2 | 0.316 |
Symptomatic PAD, % | 6.0 | 23.5 | <0.0001 |
Treatment before index stroke | |||
Antiplatelets, % | 25.2 | 28.4 | 0.651 |
Statins, % | 28.6 | 31.3 | 0.664 |
Antihypertensive, % | 62.2 | 60.3 | 0.788 |
Hypoglycemics, % | 26.9 | 36.4 | 0.139 |
Treatment at discharge | |||
Antiplatelets, % | 99.3 | 100 | 0.628 |
Statins, % | 73.8 | 73.5 | 0.533 |
Antihypertensive, % | 76.8 | 76.1 | 0.505 |
Hypoglycemics, % | 33.0 | 35.3 | 0.404 |
Stroke subtype | <0.0001 | ||
Atherothrombotic probable, % | 14.8 | 35.3 | |
Atherothrombotic posible, % | 43.7 | 41.2 | |
Lacunar, % | 21.0 | 13.2 | |
Cryptogenic, % | 20.5 | 10.3 | |
Modified Rankin at discharge | 1 [0, 2] | 2 [1, 2] | 0.034 |
ABI | 1.00 ± 0.23 | 0.92 ± 0.29 | <0.0001 |
IMT, mm | 0.91 ± 0.34 | 0.96 ± 0.44 | 0.043 |
ICA stenosis > 50 % homolateral, % | 14.8 | 35.8 | <0.0001 |
ICA stenosis > 50 % contralateral, % | 5.7 | 16.4 | 0.004 |
Echogenicity of plaques | 0.493 | ||
Type I, % | 15.0 | 10.7 | |
Type II, % | 14.7 | 17.9 | |
Type III, % | 24.5 | 21.4 | |
Type IV, % | 37.9 | 46.4 | |
Type V, % | 8.2 | 3.6 | |
Plaques surface | 0.001 | ||
Smooth and even, % | 75.0 | 50.0 | |
Uneven, % | 23.7 | 48.3 | |
Ulcerated, % | 1.3 | 1.7 | |
8-OHDG (ng/mL) | 33.11 ± 15.18 | 40.06 ± 24.70 | 0.003 |
Cu/Zn SOD (ng/mL) | 44.37[31.06-70.06] | 52.75 [36.73-89.59] | 0.062 |
ox-LDL (ng/mL) | 54.83 [45.71-69.36] | 53.43[43.34-62.52] | 0.241 |