Skip to main content

Table 3 Included biomarkers in the project categorized by reflecting Aβ or neuronal injury

From: Diagnostic and economic evaluation of new biomarkers for Alzheimer’s disease: the research protocol of a prospective cohort study

Technique

Aβ accumulation

Neuronal dysfunction

CSF

Amyloid β42 in the CSF

total tau and phosphorylated-tau in CSF

PET

amyloid tracer uptake in PET

fluorodeoxyglucose PET

MRI

 

White matter integrity (DTI)

Functional connectivity (rsfMRI)

Whole brain volume

  

Hippocampal volume

  1. Abbreviations: Aβ, beta-amyloid protein; CSF, cerebrospinal fluid; DTI, diffusion tensor imaging; MRI, magnetic resonance imaging; PET, positron emission tomography; rsfMRI, resting state functional magnetic resonance imaging.