Patients with painful neuropathies (N = 31,688) | Comparison group (N = 31,688) | P-Value | |
---|---|---|---|
Characteristic | --- | ||
Age group, years | |||
18-44 | 8,621 (27.2) | 8,621 (27.2) | |
45-54 | 6,056 (19.1) | 6,056 (19.1) | |
55-64 | 6,577 (20.8) | 6,577 (20.8) | |
≥ 65 | 10,434 (32.9) | 10,434 (32.9) | |
Mean (SD) | 56.1 (16.6) | 56.1 (16.6) | --- |
Sex | --- | ||
Males | 12,178 (38.4) | 12,178 (38.4) | |
Females | 19,510 (61.6) | 19,510 (61.6) | |
Comorbidities | |||
Infectious and parasitic diseases | 5,822 (18.4) | 3,308 (10.4) | <0.01 |
Neoplasms | 1,787 (5.6) | 1,281 (4.0) | <0.01 |
Any endocrine, nutritional and metabolic diseases, and immunity disorders | 10,699 (33.8) | 7,604 (24.0) | <0.01 |
Diseases of the blood and blood-forming organs | 2,487 (7.8) | 1,507 (4.8) | <0.01 |
Any anxiety | 897 (2.8) | 547 (1.7) | <0.01 |
Any depression | 1,365 (4.3) | 827 (2.6) | <0.01 |
Any disease of the nervous system and sense organs | 14,691 (46.4) | 5,854 (18.5) | <0.01 |
Any disease of the circulatory system | 9,071 (28.6) | 6,837 (21.6) | <0.01 |
Any disease of the respiratory system | 10,485 (33.1) | 7,786 (24.6) | <0.01 |
Any disease of the digestive system | 9,970 (31.5) | 5,488 (17.3) | <0.01 |
Any disease of the genitourinary system | 5,019 (15.8) | 3,497 (11.0) | <0.01 |
Complications of pregnancy, childbirth, and the puerperium | 325 (1.0) | 241 (0.8) | <0.01 |
Any disease of the skin and subcutaneous tissue | 9,773 (30.8) | 7,136 (22.5) | <0.01 |
Diseases of the musculoskeletal system and connective tissue | |||
Back pain | 15,444 (48.7) | 693 (2.2) | <0.01 |
Cervical pain | 2,011 (6.3) | 615 (1.9) | <0.01 |
Arthritis | 2,116 (6.7) | 1,203 (3.8) | <0.01 |
Fibromyalgia | 76 (0.2) | 11 (0.0) | <0.01 |
Other body/joint pain | 10,481 (33.1) | 3,832 (12.1) | <0.01 |
Other | 1,993 (6.3) | 917 (2.9) | <0.01 |
Any disease of the musculoskeletal system and connective tissue | 23,529 (74.3) | 6,233 (19.7) | <0.01 |
Congenital anomalies | 81 (0.3) | 44 (0.1) | <0.01 |
Symptoms, signs, and ill- defined conditions | |||
Fatigue | 16 (0.1) | 12 (0.0) | 0.45 |
Headache | 392 (1.2) | 79 (0.2) | <0.01 |
Chest pain | 387 (1.2) | 216 (0.7) | <0.01 |
Abdominal pain | 640 (2.0) | 351 (1.1) | <0.01 |
Anxiety-related symptoms | 0 (0.0) | 0 (0.0) | --- |
Gastric-related symptoms | 3 (0.0) | 1 (0.0) | 0.32 |
Other | 6,420 (20.3) | 2,989 (9.4) | <0.01 |
Any symptoms, signs, and ill- | 7,320 (23.1) | 3,507 (11.1) | <0.01 |
defined conditions | |||
Any injury and poisoning | 2,991 (9.4) | 2,021 (6.4) | <0.01 |
Any sleep disorder | 528 (1.7) | 257 (0.8) | <0.01 |
Any of above** | 31,447 (99.2) | 24,768 (78.2) | <0.01 |
Number of comorbidities** | <0.01 | ||
0 | 241 (0.8) | 6,920 (21.8) | |
1 | 3,632 (11.5) | 6,757 (21.3) | |
2 | 4,617 (14.6) | 5,648 (17.8) | |
3 | 4,883 (15.4) | 4,222 (13.3) | |
≥ 4 | 18,315 (57.8) | 8,141 (25.7) |